Multi-specific Fab fusion proteins comprising a CD3-binding Fab fragment with N-terminal fusion to binding domains and methods of use
H Zhou - US Patent 11,013,800, 2021 - Google Patents
The present disclosure relates generally to multi-specific Fab fusion proteins (MSFP) which
comprise an antibody Fab fragment with both N-termini fused to a fusion moiety (fusion …
comprise an antibody Fab fragment with both N-termini fused to a fusion moiety (fusion …
Integrated system architectures and methods of use
NJ Kemp, TK Glynn - US Patent 11,141,063, 2021 - Google Patents
US11141063B2 - Integrated system architectures and methods of use - Google Patents
US11141063B2 - Integrated system architectures and methods of use - Google Patents …
US11141063B2 - Integrated system architectures and methods of use - Google Patents …
Deep vein thrombosis therapeutic methods
J Unser, JE Brown, MP Margolis… - US Patent 11,040,140, 2021 - Google Patents
The invention provides methods for diagnosing and treating deep vein thrombosis and other
conditions associated with occluded or constricted vessels. According to certain aspects …
conditions associated with occluded or constricted vessels. According to certain aspects …
Rotational ultrasound imaging catheter with extended catheter body telescope
D Meyer, D Van Hoven - US Patent 10,993,694, 2021 - Google Patents
The present invention generally relates to devices for imaging the interior of a vessel. The
device can involve an elongated body configured to fit within the lumen of a vessel, a …
device can involve an elongated body configured to fit within the lumen of a vessel, a …
Aspirating and removing biological material
TK Glynn, J Stigall, M Minas - US Patent 10,939,826, 2021 - Google Patents
The invention generally relates to devices and methods for imaging and aspirating
biological material from inside a vessel. In certain embodiments, the invention provides …
biological material from inside a vessel. In certain embodiments, the invention provides …
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
LA Snyder, G Powers, EZ Ubani… - US Patent 11,014,987, 2021 - Google Patents
2017-08-10 Assigned to JANSSEN PHARMACEUTICA NV reassignment JANSSEN
PHARMACEUTICA NV ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
PHARMACEUTICA NV ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Vista modulators for diagnosis and treatment of cancer
RJ Noelle - US Patent 11,180,557, 2021 - Google Patents
The present disclosure relates to compositions and therapeutic methods for activating an
immune response in a patient in need thereof. In a preferred embodiment, the subject …
immune response in a patient in need thereof. In a preferred embodiment, the subject …
Conjugated biological molecules, pharmaceutical compositions and methods
MN Chang, JS Lai, WF Li, IJ Chen, YC Tsai… - US Patent …, 2021 - Google Patents
2018-01-29 Assigned to OBI PHARMA, INC. reassignment OBI PHARMA, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
VISTA antagonist and methods of use
RJ Noelle, S Ceeraz, I LeMercier, E Nowak… - US Patent …, 2021 - Google Patents
The present invention is directed to a peptide, multimer, conjugate, analog, derivative or
mimetic thereof that inhibits the activity of VISTA. The invention further contemplates …
mimetic thereof that inhibits the activity of VISTA. The invention further contemplates …
Use of vista agonists and antagonists to suppress or enhance humoral immunity
KA Green, L Wang, RJ Noelle, WR Green - US Patent 11,123,426, 2021 - Google Patents
Methods for alleviating the suppression of humoral immunity by myeloid-dependent
suppressor cells (MDSCs) are provided which include the administration of a VISTA …
suppressor cells (MDSCs) are provided which include the administration of a VISTA …