[HTML][HTML] A systematic literature review on obesity: Understanding the causes & consequences of obesity and reviewing various machine learning approaches used to …

M Safaei, EA Sundararajan, M Driss, W Boulila… - Computers in biology …, 2021 - Elsevier
Obesity is considered a principal public health concern and ranked as the fifth foremost
reason for death globally. Overweight and obesity are one of the main lifestyle illnesses that …

The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis

N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

The pleiotropic roles of leptin in metabolism, immunity, and cancer

P de Candia, F Prattichizzo, S Garavelli… - Journal of Experimental …, 2021 - rupress.org
The discovery of the archetypal adipocytokine leptin and how it regulates energy
homeostasis have represented breakthroughs in our understanding of the endocrine …

Cytokines in psoriasis

CC de Alcantara, EMV Reiche, ANC Simão - Advances in clinical chemistry, 2021 - Elsevier
Psoriasis is chronic, immune-mediated, inflammatory disease with a multifactorial etiology
that affects the skin tissue and causes the appearance of dry and scaly lesions of anywhere …

Low dietary fiber intake links development of obesity and lupus pathogenesis

AL Schäfer, A Eichhorst, C Hentze… - Frontiers in …, 2021 - frontiersin.org
Changed dietary habits in Western countries such as reduced fiber intake represent an
important lifestyle factor contributing to the increase in inflammatory immune-mediated …

Obesity in inflammatory bowel disease: A review of its role in the pathogenesis, natural history, and treatment of IBD

AM Johnson, EV Loftus Jr - Saudi Journal of Gastroenterology, 2021 - journals.lww.com
In contrast to previous perceptions that inflammatory bowel disease (IBD) patients are
generally malnourished and underweight, there is mounting evidence to suggest that rates …

[HTML][HTML] Ideal food pyramid for patients with rheumatoid arthritis: A narrative review

M Rondanelli, F Perdoni, G Peroni, R Caporali… - Clinical Nutrition, 2021 - Elsevier
Emerging literature suggests that diet plays an important modulatory role in rheumatoid
arthritis (RA) because diet is an environmental factor that affects inflammation, antigen …

Obesity and the risk of Multiple Sclerosis. The role of Leptin

M Marrodan, MF Farez… - Annals of Clinical …, 2021 - Wiley Online Library
Objective To investigate the effects of leptin on different T‐cell populations, in order to gain
more insight into the link between leptin and obesity. Methods Three hundred and nine …

Body mass index and immune-related adverse events in patients on immune checkpoint inhibitor therapies: a systematic review and meta-analysis

Y Guzman-Prado, J Ben Shimol, O Samson - Cancer Immunology …, 2021 - Springer
Background As a result of the growing use of immune checkpoint inhibitors (ICIs) for treating
malignancy, immune-related adverse events (irAEs) have been increasingly reported …

Bardet–Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self‐tolerance

O Tsyklauri, V Niederlova, E Forsythe, A Prasai… - EMBO …, 2021 - embopress.org
Abstract Bardet–Biedl Syndrome (BBS) is a pleiotropic genetic disease caused by the
dysfunction of primary cilia. The immune system of patients with ciliopathies has not been …