Current and future perspectives in the treatment of multidrug-resistant Gram-negative infections

M Bassetti, J Garau - Journal of Antimicrobial Chemotherapy, 2021 - academic.oup.com
Microbial resistance is a serious threat to human health worldwide. Among the World Health
Organisation's list of priority resistant bacteria, three are listed as critical—the highest level of …

Therapeutic options for metallo-β-lactamase-producing enterobacterales

X Tan, HS Kim, K Baugh, Y Huang… - Infection and drug …, 2021 - Taylor & Francis
The spread of metallo-β-lactamase (MBL)-producing Enterobacterales worldwide without
the simultaneous increase in active antibiotics makes these organisms an urgent public …

Carbapenemase-producing Enterobacteriaceae in transplant patients

M Giannella, M Bartoletti, M Conti… - Journal of Antimicrobial …, 2021 - academic.oup.com
Carbapenemase-producing Enterobacteriaceae (CPE) are a serious public health concern
and represent a major threat to immunocompromised hosts, including solid organ (SOT) and …

Fosfomycin and nitrofurantoin: classic antibiotics and perspectives

C Dos Santos, LS Dos Santos, OL Franco - The Journal of Antibiotics, 2021 - nature.com
Antibiotics are essential molecules for the treatment and prophylaxis of many infectious
diseases. However, drugs that combat microbial infections can become a human health …

Clinical outcomes of temocillin use for invasive Enterobacterales infections: a single-centre retrospective analysis

KL Heard, K Killington, N Mughal… - JAC-Antimicrobial …, 2021 - academic.oup.com
Background With increasing frequency of resistant Gram-negative bacteria, temocillin has
potential utility in reducing carbapenem use. The 2020 EUCAST guideline changes …

Fosfomycin in continuous or prolonged infusion for systemic bacterial infections: a systematic review of its dosing regimen proposal from in vitro, in vivo and clinical …

RM Antonello, S Di Bella, AE Maraolo… - European Journal of …, 2021 - Springer
Fosfomycin (FOS) administered intravenously has been recently rediscovered for the
treatment of systemic infections due to multidrug-resistant bacteria. Its pharmacokinetic …

Retrospective evaluation of intravenous fosfomycin in multi-drug resistant infections at a tertiary care hospital in Lebanon

T Ballouz, RM Zeenny, N Haddad, N Rizk… - The Journal of Infection in …, 2021 - jidc.org
Introduction: Fosfomycin has re-emerged as a possible therapeutic alternative for the
treatment of resistant bacterial pathogens. Its main mechanism of action is the inhibition of …

[HTML][HTML] A real-world study on prescription pattern of fosfomycin in critical care patients

KG Zirpe, Y Mehta, R Pandit, R Pande… - Indian Journal of …, 2021 - ncbi.nlm.nih.gov
A Real-world Study on Prescription Pattern of Fosfomycin in Critical Care Patients - PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

New perspectives in the antibiotic treatment of mechanically ventilated patients with infections from Gram-negatives

M Karvouniaris, K Pontikis, T Nitsotolis… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Ventilator-associated pneumonia (VAP) is a common and potentially fatal
complication of mechanical ventilation that is often caused by multidrug-resistant (MDR) …

Fosfomycin-trometamol (FT) or fluoroquinolone (FQ) as single-dose prophylaxis for transrectal ultrasound-guided prostate biopsy (TRUS-PB): A prospective cohort …

T Delory, A Goujon, A Masson-Lecomte, P Arias… - International Journal of …, 2021 - Elsevier
Objectives The increasing incidence of fluoroquinolones (FQ) resistance may lower its
efficacy in preventing UTI following transrectal ultrasound-guided prostate biopsy (TRUS …