[HTML][HTML] Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

[HTML][HTML] Role of somatostatin receptor in pancreatic neuroendocrine tumor development, diagnosis, and therapy

Y Hu, Z Ye, F Wang, Y Qin, X Xu, X Yu… - Frontiers in …, 2021 - frontiersin.org
Pancreatic neuroendocrine tumors (pNETs) are rare and part of the diverse family of
neuroendocrine neoplasms (NENs). Somatostatin receptors (SSTRs), which are widely …

[HTML][HTML] Radiomics-Based Texture Analysis of 68Ga-DOTATATE Positron Emission Tomography and Computed Tomography Images as a Prognostic Biomarker in Adults With …

C Atkinson, B Ganeshan, R Endozo, S Wan… - Frontiers in …, 2021 - frontiersin.org
Purpose Neuroendocrine tumors (NET) are rare cancers with variable behavior. A better
understanding of prognosis would aid individualized management. The aim of this …

Translational challenges in pancreatic neuroendocrine tumor immunotherapy

ESA Egal, D Jacenik, HP Soares, EJ Beswick - Biochimica et Biophysica …, 2021 - Elsevier
Pancreatic neuroendocrine tumors are rare types of pancreatic cancer formed from islet cells
of pancreas. Clinical presentation of pancreatic neuroendocrine tumors depends on both …

[HTML][HTML] Correlation of Somatostatin Receptor 1–5 Expression, [68Ga]Ga-DOTANOC, [18F]F-FDG PET/CT and Clinical Outcome in a Prospective Cohort of …

S Majala, T Vesterinen, H Seppänen, H Mustonen… - Cancers, 2021 - mdpi.com
Simple Summary The need for prognostic and predictive biomarkers in pancreatic
neuroendocrine neoplasms (PNENs) is great. Overexpression of somatostatin receptors …

Driver mutations occur frequently in metastases of well‐differentiated small intestine neuroendocrine tumours

KG Samsom, S Levy, LM van Veenendaal… - …, 2021 - Wiley Online Library
Aims To investigate the clinicopathological significance of driver mutations in metastatic well‐
differentiated small intestine neuroendocrine tumours (SI‐NETs). Methods and results …

Quantitative digital image analysis of somatostatin receptor 2 immunohistochemistry in pancreatic neuroendocrine tumors

H Watanabe, R Ide, Y Yamazaki, F Fujishima… - Medical Molecular …, 2021 - Springer
Immunohistochemical analysis of somatostatin receptor 2 (SSTR2) provides important
information regarding the potential therapeutic efficacy of somatostatin analogues (SSAs) in …

Upregulation of Somatostatin Receptor 2 in Neuroendocrine Tumors Using Histone Deacetylase Inhibitors

R Guenter - 2021 - search.proquest.com
Neuroendocrine cancer is complex disease of the diffuse neuroendocrine system.
Neuroendocrine tumors (NETs) can arise throughout the body, including the lungs and …

Szomatosztatin receptorok, mint molekuláris targetek vizsgálata humán uvealis melanomában és gyermekkori hematológiai-onkológiai kórképekben

KM Harda - dea.lib.unideb.hu
A születéskor várható élettartam folyamatos emelkedést mutat a világ minden régiójában.
Azonban vannak olyan betegségek, amelyek korábban jóval kisebb esetszámmal és …

[PDF][PDF] Correlation of Somatostatin Receptor 1–5 Expression,[68Ga] Ga-DOTANOC,[18F] F-FDG PET/CT and Clinical Outcome in a Prospective Cohort of Pancreatic …

S Majala, T Vesterinen, H Seppänen, H Mustonen… - 2021 - helda.helsinki.fi
Purpose: The aim of this study was to correlate immunohistochemical (IHC) tissue levels of
SSTR1-5 with the receptor density generated from [68Ga] Ga-DOTANOC uptake in a …