[HTML][HTML] Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

[HTML][HTML] Cryptococcus neoformans and Cryptococcus gattii Species Complexes in Latin America: A Map of Molecular Types, Genotypic Diversity, and Antifungal …

C Firacative, W Meyer, E Castañeda - Journal of Fungi, 2021 - mdpi.com
Cryptococcosis, a potentially fatal mycosis, is caused by members of the Cryptococcus
neoformans and Cryptococcus gattii species complexes. In Latin America, cryptococcal …

Cryptococcal meningitis: a review for emergency clinicians

KM Fisher, T Montrief, M Ramzy, A Koyfman… - Internal and emergency …, 2021 - Springer
Abstract Introduction Cryptococcal Meningitis (CM) remains a high-risk clinical condition,
and many patients require emergency department (ED) management for complications and …

Outcomes in previously healthy cryptococcal meningoencephalitis patients treated with pulse taper corticosteroids for post-infectious inflammatory syndrome

S Anjum, O Dean, P Kosa, MT Magone… - Clinical Infectious …, 2021 - academic.oup.com
Background Cryptococcal meningoencephalitis (CM) is a major cause of mortality in
immunosuppressed patients and previously healthy individuals. In the latter, a post …

[HTML][HTML] Central nervous system infections in immunocompromised patients

AA Pruitt - Current neurology and neuroscience reports, 2021 - Springer
Abstract Purpose of Review This article reviews current epidemiologic trends, clinical
presentations, and diagnostic strategies for central nervous system (CNS) infections in …

Rational design of oral flubendazole-loaded nanoemulsion for brain delivery in cryptococcosis

MN Yukuyama, K Ishida, GLB de Araujo… - Colloids and Surfaces A …, 2021 - Elsevier
Cryptococcal meningitis is caused by Cryptococcus spp. and predominantly affects patients
with acquired immunodeficiency syndrome. However, an increase in the number of nonHIV …

CCR2 signaling promotes brain infiltration of inflammatory monocytes and contributes to neuropathology during cryptococcal meningoencephalitis

J Xu, A Ganguly, J Zhao, M Ivey, R Lopez… - MBio, 2021 - Am Soc Microbiol
Cryptococcal meningoencephalitis (CM) is a leading cause of central nervous system (CNS)
infection-related mortality worldwide, with surviving patients often developing neurological …

Cryptococcus gattii species complex as an opportunistic pathogen: underlying medical conditions associated with the infection

DH Yang, MR England, H Salvator, S Anjum, YD Park… - MBio, 2021 - Am Soc Microbiol
The Cryptococcus gattii species complex has often been referred to as a primary pathogen
due to its high infection frequency among apparently immunocompetent patients. In order to …

[HTML][HTML] Cryptococcal meningitis and post-infectious inflammatory response syndrome in a patient with X-linked hyper IgM syndrome: a case report and review of the …

L Romani, PR Williamson, S Di Cesare… - Frontiers in …, 2021 - frontiersin.org
The hyper IgM syndromes are a rare group of primary immunodeficiency. The X-linked
Hyper IgM syndrome (HIGM), due to a gene defect in CD40L, is the commonest variant; it is …

Cryptococcal meningitis in non-HIV patients in the State of Amazonas, Northern Brazil

SB Pinheiro, ES Sousa, ACA Cortez… - Brazilian Journal of …, 2021 - Springer
Cryptococcosis is a life-threatening fungal infection caused by the Cryptococcus
neoformans/Cryptococcus gattii species complex. Most cases are recorded in patients …