Familial pulmonary fibrosis: genetic features and clinical implications
D Zhang, CA Newton - Chest, 2021 - Elsevier
Pulmonary fibrosis comprises a wide range of fibrotic lung diseases with unknown
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …
[HTML][HTML] A model of the aged lung epithelium in idiopathic pulmonary fibrosis
H Shaghaghi, K Cuevas-Mora, R Para, C Tran… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is an age-related disorder that carries a universally poor
prognosis and is thought to arise from repetitive micro injuries to the alveolar epithelium. To …
prognosis and is thought to arise from repetitive micro injuries to the alveolar epithelium. To …
Molecular chaperone ability to inhibit amyloid-derived neurotoxicity, but not amorphous protein aggregation, depends on a conserved pH-sensitive Asp residue
Proteins can self-assemble into amyloid fibrils or amorphous aggregates and thereby cause
disease. Molecular chaperones can prevent both these types of protein aggregation, but the …
disease. Molecular chaperones can prevent both these types of protein aggregation, but the …
Pathogenicity prediction of single amino acid variants with machine learning model based on protein structural energies
The most popular tools for predicting pathogenicity of single amino acid variants (SAVs)
were developed based on sequence-based techniques. SAVs may change protein structure …
were developed based on sequence-based techniques. SAVs may change protein structure …
[PDF][PDF] Genetische und molekularbiologische Prädiktoren für die Krankheitsprogression der idiopathischen Lungenfibrose
C Caliskan - 2021 - mhh-publikationsserver.gbv.de
Die Lungenfibrose beschreibt eine Vermehrung von Fibroblasten und extrazellulärer Matrix
im Interstitium und im Alveolarraum. Dieses Phänomen ist nicht spezifisch und kann bei …
im Interstitium und im Alveolarraum. Dieses Phänomen ist nicht spezifisch und kann bei …