Perioperative pain management and opioid stewardship: a practical guide

SJ Hyland, KK Brockhaus, WR Vincent, NZ Spence… - Healthcare, 2021 - mdpi.com
Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery

B Doleman, J Leonardi-Bee, TP Heinink… - Cochrane Database …, 2021 - cochranelibrary.com
Background Postoperative pain is a common consequence of surgery and can have many
negative perioperative effects. It has been suggested that the administration of analgesia …

[HTML][HTML] Methodologies for systematic reviews with meta-analysis of randomised clinical trials in pain, anaesthesia, and perioperative medicine

B Doleman, O Mathiesen, JC Jakobsen… - British Journal of …, 2021 - Elsevier
Systematic reviews and meta-analyses (SRMAs) are increasing in popularity, but should
they be used to inform clinical decision-making in anaesthesia? We present evidence that …

[HTML][HTML] Respiratory depression in the post-anesthesia care unit: Mayo Clinic experience

ML Laporta, J Sprung… - Bosnian journal of basic …, 2021 - ncbi.nlm.nih.gov
The anesthesia recovery is a complex physiologic process as systems recover from the
effects of surgery and anesthesia. Inadequate recovery of respiratory physiology can lead to …

Study protocol: randomized controlled trial of opioid-free vs. traditional perioperative analgesia in elective orthopedic surgery

EZ Shing, D Leas, C Michalek, MK Wally… - BMC Musculoskeletal …, 2021 - Springer
Background The medical community is beginning to recognize the contribution of
prescription opioids in the growing national opioid crisis. Many studies have compared the …

Pharmacologically induced ventilatory depression in the postoperative patient: a sleep-wake state-dependent perspective

AG Doufas, TN Weingarten - Anesthesia & Analgesia, 2021 - journals.lww.com
Pharmacologically induced ventilatory depression (PIVD) is a common postoperative
complication with a spectrum of severity ranging from mild hypoventilation to severe …

Meta‐analyses of gabapentinoids for pain management after knee arthroplasty: A caveat emptor? A narrative review

GP Joshi, H Kehlet - Acta Anaesthesiologica Scandinavica, 2021 - Wiley Online Library
The use of gabapentinoids for perioperative pain management after total knee arthroplasty
has been the subject of nine systematic reviews and meta‐analyses. A critical analysis of the …

Preoperative gabapentin administration and its impact on postoperative opioid requirement and pain in sinonasal surgery

AS Gill, FR Virani, JC Hwang… - … –Head and Neck …, 2021 - journals.sagepub.com
Objective To determine the efficacy of preoperative gabapentin on patient-reported pain
levels and postoperative opioid requirements following sinonasal surgery. Study Design …

Preoperative gabapentin versus bisoprolol for haemodynamic and surgical field optimisation during endoscopic sinus surgery: A randomised controlled trial

AM Elnakera, MH Wagdy, AA Abd-Elgelyl… - Indian Journal of …, 2021 - journals.lww.com
Methods: Patients were assigned into one of three groups. Patients of gabapentin group
received preoperative oral gabapentin 1200 mg while, patients of bisoprolol and control …

[HTML][HTML] Effects of Pre-Operative Single Dose Gabapentin on Postoperative Pain Following Total Abdominal Hysterectomy: A Dose Finding Study

A Kumar, G Afshan, T Naru - Open Journal of Anesthesiology, 2021 - scirp.org
Background & Aims: The multimodal analgesia provides superior pain relief and reduces
opioid consumption and its side effects. Gabapentin has been used successfully in multi …