Flavonoids as antiobesity agents: A review

AT Rufino, VM Costa, F Carvalho… - Medicinal Research …, 2021 - Wiley Online Library
Obesity is a global health problem that affects all age groups in both developing and
developed countries. In recent years, the prevalence of overweight and obesity has reached …

Drug-induced liver injury: highlights and controversies in the recent literature

JW Clinton, S Kiparizoska, S Aggarwal, S Woo… - Drug safety, 2021 - Springer
Drug-induced liver injury (DILI) remains an important, yet challenging diagnosis for
physicians. Each year, additional drugs are implicated in DILI and this year was no different …

Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled …

V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte… - Nature Medicine, 2021 - nature.com
Fecal microbial transplantation (FMT) from lean donors to patients with obesity has been
associated with metabolic benefits, yet results so far have been inconsistent. In this study …

Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: a randomised, double-blind, placebo-controlled …

IJ Neeland, SP Marso, CR Ayers, B Lewis… - The lancet Diabetes & …, 2021 - thelancet.com
Background Visceral and ectopic fat are key drivers of adverse cardiometabolic outcomes in
obesity. We aimed to evaluate the effects of injectable liraglutide 3· 0 mg daily on body fat …

Serum albumin: clinical significance of drug binding and development as drug delivery vehicle

S Tayyab, SR Feroz - Advances in protein chemistry and structural biology, 2021 - Elsevier
Human serum albumin, the primary transport and reservoir protein in the human circulatory
system, interacts with numerous endogenous and exogenous ligands of varying structural …

Gut hormones in health and obesity: the upcoming role of short chain fatty acids

H Alhabeeb, A AlFaiz, E Kutbi, D AlShahrani… - Nutrients, 2021 - mdpi.com
We are currently facing an obesity pandemic, with worldwide obesity rates having tripled
since 1975. Obesity is one of the main risk factors for the development of non-communicable …

Pharmacotherapy of obesity: An update

A Cignarella, L Busetto, R Vettor - Pharmacological research, 2021 - Elsevier
Several pharmacological approaches to controlling body weight have been developed over
the last decades, albeit with limited success. Currently available agents include centrally …

Contemporary classification of glucagon-like peptide 1 receptor agonists (GLP1RAs)

S Kalra, S Bhattacharya, N Kapoor - Diabetes Therapy, 2021 - Springer
This communication provides a contemporary classification of glucagon-like peptide 1
receptor agonists (GLP1RAs) based on indication, route, and frequency of administration …

The best drug supplement for obesity treatment: a systematic review and network meta-analysis

N Salari, S Jafari, N Darvishi, E Valipour… - Diabetology & Metabolic …, 2021 - Springer
Background Obesity is a complex disease with an increasing prevalence worldwide. There
are different weight-management options for obesity treatment, including dietary control …

A systematic review of the European rapid alert system for food and feed: tendencies in illegal food supplements for weight loss

D Koncz, B Tóth, O Roza, D Csupor - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: Slimming products represent a dynamically growing group of food
supplements worldwide. The efficacy of safely usable natural ingredients is usually below …