Degeneration and death of motor neurons in Amyotrophic Lateral Sclerosis (ALS) are
associated with increased lipid peroxidation. Lipid peroxidation is the driver of ferroptosis …

Abstract Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment
operating at static magnetic field of 7 tesla (7 T) and above, enable the acquisition of data …

Circulating cell-free DNA (cfDNA) in the bloodstream originates from dying cells and is a
promising noninvasive biomarker for cell death. Here, we propose an algorithm, CelFiE, to …

Purpose: The main purpose of this study was to create an empirical classification system for
speech severity in patients with dysarthria secondary to amyotrophic lateral sclerosis (ALS) …

Objective: Understanding clinical variants of motor neuron diseases such as amyotrophic
lateral sclerosis (ALS) is critical for discovering disease mechanisms and across-patient …

Cigarette smoke (CS) has been consistently demonstrated to be an environmental risk factor
for amyotrophic lateral sclerosis (ALS), although the molecular pathogenic mechanisms …

2015). Actualmente, se estima que hasta el 50% de los afectados de ELA muestran algún
signo sutil de deterioro cognitivo y/o conductual y, hasta el 15% cumplen los criterios de …

Background: Amyotrophic lateral sclerosis (ALS), like many neurodegenerative conditions,
lacks definitive biomarkers for disease diagnosis, prognosis, staging and measurement of …

Abstract About 10% of Amyotrophic Lateral Sclerosis (ALS) cases can be explained by
mutation in a gene. Human induced pluripotent stem cells enable to conduct research of …