Neurovascular reactivity in the aging mouse brain assessed by laser speckle contrast imaging and 2-photon microscopy: quantification by an investigator-independent …

FB Seker, Z Fan, B Gesierich, M Gaubert… - Frontiers in …, 2021 - frontiersin.org
The brain has a high energy demand but little to no energy stores. Therefore, proper brain
function relies on the delivery of glucose and oxygen by the cerebral vasculature. The …

Microscopic quantification of oxygen consumption across cortical layers

P Mächler, N Fomin-Thunemann, M Thunemann… - bioRxiv, 2021 - biorxiv.org
The cerebral cortex is organized in cortical layers that differ in their cellular density,
composition, and wiring. Cortical laminar architecture is also readily revealed by staining for …

Response to Hypoxia in Cognitive Decline

JW Larrick, JW Larrick, AR Mendelsohn - Rejuvenation Research, 2021 - liebertpub.com
Inflammaging, the increase of proinflammatory processes with increasing age, has multiple
mechanisms from increasing numbers of senescent cells secreting cytokines to changes in …