Novel Nano‐Based Drug Delivery Systems Targeting Hepatic Stellate Cells in the Fibrotic Liver
D Ezhilararasan, T Lakshmi, B Raut - Journal of Nanomaterials, 2021 - Wiley Online Library
Hepatic stellate cells (HSCs) exist in the liver's perisinusoidal space, are phenotypically
activated, and acquire myofibroblast‐like phenotype. This phenotypic transformation is …
activated, and acquire myofibroblast‐like phenotype. This phenotypic transformation is …
Utilization of PEGylated cerosomes for effective topical delivery of fenticonazole nitrate: in-vitro characterization, statistical optimization, and in-vivo assessment
In this investigation, we focused on ceramide IIIB, a skin component whose depletion tends
to augment multiple skin disorders and fungal infections. Ceramide IIIB was included into …
to augment multiple skin disorders and fungal infections. Ceramide IIIB was included into …
Phospholipid/zein hybrid nanoparticles as promising carriers for the protection and delivery of all-trans retinoic acid
A Gagliardi, S Voci, E Giuliano, MC Salvatici… - Materials Science and …, 2021 - Elsevier
A totally biodegradable mixed system made up of phospholipids and zein was developed in
order to effectively improve the photostability of all-trans retinoic acid (ATRA) preserving its …
order to effectively improve the photostability of all-trans retinoic acid (ATRA) preserving its …
Voriconazole ternary micellar systems for the treatment of ocular mycosis: statistical optimization and in vivo evaluation
Voriconazole (VRC) is a broad spectrum, second generation triazole antifungal. The main
use of VRC is via the oral and intravenous route. The study aimed to formulate VRC into …
use of VRC is via the oral and intravenous route. The study aimed to formulate VRC into …
Diacerein solid dispersion loaded tablets for minimization of drug adverse effects: statistical design, formulation, in vitro, and in vivo evaluation
MAN Soliman, HK Ibrahim… - Pharmaceutical …, 2021 - Taylor & Francis
Diacerein is a BCS class II drug employed in osteoarthritis management. The acid/base
hydrolysis of the unabsorbed diacerein in the colon is responsible for its laxative effect …
hydrolysis of the unabsorbed diacerein in the colon is responsible for its laxative effect …
Advances on Nanomedicines for Diagnosis and Theranostics of Hepatic Fibrosis
X Dai, Y Zeng, H Zhang, Z Gu… - Advanced NanoBiomed …, 2021 - Wiley Online Library
Hepatic fibrosis is induced by chronic hepatic injuries before it turns into hepatic
cirrhosis/carcinoma. It is characterized by the formation of collagen and other extracellular …
cirrhosis/carcinoma. It is characterized by the formation of collagen and other extracellular …