New perspectives on antimicrobial agents: cefiderocol

EK McCreary, EL Heil, PD Tamma - Antimicrobial agents and …, 2021 - Am Soc Microbiol
Bacterial resistance to carbapenem agents has reached alarming levels. Accordingly,
collaborative efforts between national and international organizations and the …

[HTML][HTML] Comparative efficacy and safety of combination therapy with high-dose sulbactam or colistin with additional antibacterial agents for multiple drug-resistant and …

J Liu, Y Shu, F Zhu, B Feng, Z Zhang, L Liu… - Journal of global …, 2021 - Elsevier
Objectives This study aimed to compare the efficacy and safety of combination therapy with
high-dose sulbactam or colistin with additional antibacterial agents for treating multidrug …

Treatment of patients with serious infections due to carbapenem‐resistant Acinetobacter baumannii: How viable are the current options?

JN O'Donnell, V Putra, TP Lodise - … : The Journal of Human …, 2021 - Wiley Online Library
This review critically appraises the published microbiologic and clinical data on the
treatment of patients with carbapenem‐resistant Acinetobacter baumannii infections …

Systematic review and meta-analysis of the proportion and associated mortality of polymicrobial (vs monomicrobial) pulmonary and bloodstream infections by …

S Karakonstantis, EI Kritsotakis - Infection, 2021 - Springer
Abstract Background Differentiating Acinetobacter baumannii complex (ABC) infection from
colonization remains difficult and further complicated in polymicrobial infections. Purpose To …

Comparative metabolomics reveals key pathways associated with the synergistic activity of polymyxin B and rifampicin combination against multidrug-resistant …

J Zhao, ML Han, Y Zhu, YW Lin, YW Wang, J Lu… - Biochemical …, 2021 - Elsevier
Multidrug-resistant (MDR) Acinetobacter baumannii presents a critical challenge to human
health worldwide and polymyxins are increasingly used as a last-line therapy. Due to the …

[HTML][HTML] What is the optimal antibiotic treatment strategy for carbapenem-resistant Acinetobacter baumannii (CRAB)? A multicentre study in Korea

H Seok, WS Choi, S Lee, C Moon, DW Park… - Journal of Global …, 2021 - Elsevier
Objectives The optimal treatment option for carbapenem-resistant Acinetobacter baumannii
(CRAB) is still limited. This study investigated the efficacy of three or more antibiotic types …

[HTML][HTML] Polymyxin monotherapy vs. combination therapy for the treatment of multidrug-resistant infections: a systematic review and meta-analysis

S Samal, SB Samir, SK Patra, A Rath… - Indian journal of …, 2021 - ncbi.nlm.nih.gov
Polymyxin Monotherapy vs. Combination Therapy for the Treatment of Multidrug-resistant
Infections: A Systematic Review and Meta-analysis - PMC Back to Top Skip to main content NIH …

Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii

RR McCarthy, GJ Larrouy-Maumus… - … : Infection and Immunity, 2021 - Springer
The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare
systems around the world revolutionised global health. It marked the beginning of a golden …

[PDF][PDF] Current aspects of antibacterial drug administration when treating nosocomial Pneumonia

IM Farber, MA Kudryashova, LA Galstyan… - Journal of Advanced …, 2021 - japer.in
The article presents a literature review on the current aspects of antibacterial drug
administration when treating nosocomial pneumonia. Current data are presented regarding …

Novel Peptide-Based Therapeutics Against Gram-Negative Pathogens

V Selvarajan - 2021 - search.proquest.com
Over the years, peptides have evolved as viable drug leads in research & development for
different biomedical applications. The importance of developing peptides as potent …