Nephrotoxicity from molecularly targeted chemotherapeutic agents

J Kala, LA Salman, AS Geara, H Izzedine - Advances in Chronic Kidney …, 2021 - Elsevier
The introduction of novel molecularly targeted therapies in the last 2 decades has
significantly improved the patient survival compared to standard conventional …

Review of intravitreal VEGF inhibitor toxicity and report of collapsing FSGS with TMA in a patient with age-related macular degeneration

G Phadke, RM Hanna, A Ferrey, EA Torres… - Clinical kidney …, 2021 - academic.oup.com
Intravitreal vascular endothelial growth factor (VEGF) receptor blockade is used for a variety
of retinal pathologies. These include age-related macular degeneration (AMD), diabetic …

[HTML][HTML] Nintedanib-induced renal thrombotic microangiopathy

T Fujita, H Nakagawa, T Yokota, J Umetani… - Case Reports in …, 2021 - karger.com
Nintedanib is a unique tyrosine kinase inhibitor used to suppress fibrosis in patients with
idiopathic pulmonary fibrosis (IPF). Nintedanib has been shown to suppress multiple …

[PDF][PDF] Nephrotoxicity induced by vascular endothelial growth factor inhibitors

S Badri, L Siberian, R Soltani… - Journal of …, 2021 - jnephropharmacology.com
Vascular endothelial growth factor (VEGF) is a special mitogen for vascular endothelial cells,
an essential endogenous angiogenic cytokine, and the principal controller of vascular …

[HTML][HTML] Angiogenesis inhibitors as anti-cancer therapy following renal transplantation: a case report and review of the literature

L Kasherman, J Doi, K Karakasis, J Schiff, A Kitchlu… - Current …, 2021 - mdpi.com
Solid organ transplant recipients on long-term immunosuppressive medication are at
increased risk of developing malignancy, and treatment of advanced cancers with …

Pathologic Correlation with Renal Dysfunction after Intravitreal Injections of Vascular Endothelial Growth Factor Antagonists

PL Zhang, S Raza, W Li… - Annals of Clinical & …, 2021 - Assoc Clin Scientists
Objective Vascular endothelial growth factor (VEGF) antagonists have been used for treating
metastatic neoplasms. It has also been known that one of its side effects is to cause …

[PDF][PDF] The retinal microvasculature as an early indicator of chronic disease risk in older populations

R O'Neill - 2021 - pure.qub.ac.uk
Vascular endothelial growth factor (VEGF), also referred to as VEGF-A is a 40–45 kDa
dimeric glycoprotein containing a cysteine knot motif (1). In addition to VEGFA, this …

[PDF][PDF] Review of intravitreal vascular endothelial growth factor inhibitor toxicity, and report of collapsing focal and segmental glomerulosclerosis with thrombotic …

G Phadke, RM Hanna, A Ferrey, EA Torres, A Singla… - 2021 - scholar.archive.org
ABSTRACT Intravitreal Vascular Endothelial Growth Factor (VEGF) Receptor blockade is
used for a variety of retinal pathologies. These include age related macular degeneration …