Relapsed/refractory multiple myeloma in 2020/2021 and beyond
K Podar, X Leleu - Cancers, 2021 - mdpi.com
Simple Summary During the last two decades, collaborative translational studies utilizing
novel methodologies have dramatically advanced our understanding of multiple myeloma …
novel methodologies have dramatically advanced our understanding of multiple myeloma …
Recent progress of exosomes in multiple myeloma: pathogenesis, diagnosis, prognosis and therapeutic strategies
X Wang, L He, X Huang, S Zhang, W Cao, F Che… - Cancers, 2021 - mdpi.com
Simple Summary In the pathogenesis of multiple myeloma (MM), some exosomes act on
different cells in the bone marrow microenvironment, which can create an environment …
different cells in the bone marrow microenvironment, which can create an environment …
Corneal changes after belantamab mafodotin in multiple myeloma patients
RB Bausell, A Soleimani, A Vinnett, MD Baroni… - Eye & Contact …, 2021 - journals.lww.com
Objectives: To describe progressive corneal microcyst-like epithelial changes (MECs) that
developed in patients treated with the investigational drug belantamab mafodotin (belamaf) …
developed in patients treated with the investigational drug belantamab mafodotin (belamaf) …
[HTML][HTML] Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography
Purpose To describe structural changes in corneal epithelium using anterior segment optical
coherence tomography (AS-OCT) in two relapsed and refractory multiple myeloma (RRMM) …
coherence tomography (AS-OCT) in two relapsed and refractory multiple myeloma (RRMM) …
Proteomics-based approach reveals the involvement of SERPINB9 in recurrent and relapsed multiple myeloma
Y Chen, L Quan, C Jia, Y Guo, X Wang… - Journal of Proteome …, 2021 - ACS Publications
Multiple myeloma (MM) is a common hematological malignancy with poorly understood
recurrence and relapse mechanisms. Notably, bortezomib resistance leading to relapse …
recurrence and relapse mechanisms. Notably, bortezomib resistance leading to relapse …
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity
Y Wang, T Mi, Y Li, W Kan, G Xu, J Li, Y Zhou… - European Journal of …, 2021 - Elsevier
Lenalidomide and its analogs are well-known for treating multiple myeloma. In this work,
designed sulfide-modified lenalidomide and pomalidomide were synthesized and …
designed sulfide-modified lenalidomide and pomalidomide were synthesized and …
Daratumumab in multiple myeloma: experience of the multiple myeloma GIMEMA Lazio group
F Vozella, A Siniscalchi, M Rizzo, T Za, G Antolino… - Annals of …, 2021 - Springer
Daratumumab (DARA) is a human IgG-K monoclonal antibody (MoAb) targeting CD38 that
is approved alone or in combination with bortezomib and dexamethasone or lenalidomide …
is approved alone or in combination with bortezomib and dexamethasone or lenalidomide …
Real-world outcomes with generic pomalidomide in relapsed refractory multiple myeloma—experience from a Tertiary Care Cancer Center
SK Bondili, B Bagal, A Zawar, P Ventrapati… - JCO Global …, 2021 - ascopubs.org
PURPOSE The prognosis of relapsed and refractory multiple myeloma (RRMM) that is
refractory to bortezomib and lenalidomide is very poor wherein the median survival is …
refractory to bortezomib and lenalidomide is very poor wherein the median survival is …
A systematic review and network meta-analysis of randomized data on efficacy of novel therapy combinations in patients with lenalidomide-refractory multiple …
Introduction Lenalidomide use in nearly all induction regimens for multiple myeloma (MM)
has led to the treatment of lenalidomide-refractory disease becoming one of the most …
has led to the treatment of lenalidomide-refractory disease becoming one of the most …
The Relationship of ABCB1/MDR1 and CYP1A1 Variants with the Risk of Disease Development and Shortening of Overall Survival in Patients with Multiple Myeloma
S Zmorzynski, M Wojcierowska-Litwin… - Journal of Clinical …, 2021 - mdpi.com
(1) Background: The aim of our study was to analyze the possible relationship of ABCB1 and
CYP1A1 gene variants with susceptibility and outcome of multiple myeloma (MM);(2) …
CYP1A1 gene variants with susceptibility and outcome of multiple myeloma (MM);(2) …