Neurodegenerative disorders of alzheimer, parkinsonism, amyotrophic lateral sclerosis and multiple sclerosis: an early diagnostic approach for precision treatment

N Pathak, SK Vimal, I Tandon, L Agrawal… - Metabolic Brain …, 2021 - Springer
Neurodegenerative diseases (NDs) are characterised by progressive dysfunction of
synapses, neurons, glial cells and their networks. Neurodegenerative diseases can be …

Mitigating inequities and saving lives with ICU triage during the COVID-19 pandemic

DB White, B Lo - American Journal of Respiratory and Critical Care …, 2021 - atsjournals.org
The burdens of the coronavirus disease (COVID-19) pandemic have fallen
disproportionately on disadvantaged groups, including the poor and Black, Latinx, and …

Impact of socioeconomic status and race on sepsis epidemiology and outcomes

E Minejima, A Wong-Beringer - The journal of applied laboratory …, 2021 - academic.oup.com
Background Socioeconomic status (SES) is a complex variable that is derived primarily from
an individual's education, income, and occupation and has been found to be inversely …

Hospital outcomes for children with severe sepsis in the USA by race or ethnicity and insurance status: a population-based, retrospective cohort study

HK Mitchell, A Reddy, D Montoya-Williams… - The Lancet Child & …, 2021 - thelancet.com
Background Disparities in outcomes of adult sepsis are well described by insurance status
and race and ethnicity. There is a paucity of data looking at disparities in sepsis outcomes in …

Aging influences the cardiac macrophage phenotype and function during steady state and during inflammation

NS Esfahani, Q Wu, N Kumar, LP Ganesan… - Aging cell, 2021 - Wiley Online Library
Aging‐mediated immune dysregulation affects the normal cardiac immune cell phenotypes
and functions, resulting in cardiac distress. During cardiac inflammation, immune activation …

Early care of adults with suspected sepsis in the emergency department and out-of-hospital environment: a consensus-based task force report

DM Yealy, NM Mohr, NI Shapiro, A Venkatesh… - Annals of emergency …, 2021 - Elsevier
Sepsis is a major cause of hospital death in the United States (US) 1 and is associated with
over 850,000 annual emergency department visits. 2 Despite advances in care, patients with …

Association of annual intensive care unit sepsis caseload with hospital mortality from sepsis in the United Kingdom, 2010-2016

R Maharaj, A McGuire, A Street - JAMA network open, 2021 - jamanetwork.com
Importance Sepsis is associated with a high burden of inpatient mortality. Treatment in
intensive care units (ICUs) that have more experience treating patients with sepsis may be …

Racial disparities in readmissions following initial hospitalization for sepsis

BD Lizza, KD Betthauser, PH Juang… - Critical care …, 2021 - journals.lww.com
OBJECTIVES: To assess whether Black race is associated with a higher rate of all-cause
readmission compared with White race following community-onset sepsis. DESIGN …

Lower socioeconomic factors are associated with higher mortality in patients with septic shock

DC Hidalgo, N Tapaskar, S Rao, D Masic, A Su… - Heart & Lung, 2021 - Elsevier
Background Previous studies have explored the relationship between socioeconomic status
and sepsis outcomes Objectives The purpose of this investigation is to determine if race …

Computed tomography for detection of septic foci: Retrospective analysis of patients presenting to the emergency department

J Pohlan, D Witham, G Muench, HJ Kwon… - Clinical Imaging, 2021 - Elsevier
Objective Sepsis is defined as organ dysfunction due to severe infection. Septic patients
face a significant mortality risk. Thus, timely recognition with prompt focus identification and …