[HTML][HTML] Mechanistic Understanding of Candida albicans Biofilm Formation and Approaches for Its Inhibition

T Atriwal, K Azeem, FM Husain, A Hussain… - Frontiers in …, 2021 - frontiersin.org
In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Alternatives to conventional antibiotic therapy: potential therapeutic strategies of combating antimicrobial-resistance and biofilm-related infections

Q Xu, X Hu, Y Wang - Molecular biotechnology, 2021 - Springer
Antibiotics have been denoted as the orthodox therapeutic agents for fighting bacteria-
related infections in clinical practices for decades. Nevertheless, overuse of antibiotics has …

[HTML][HTML] Back to Nature: Combating Candida albicans Biofilm, Phospholipase and Hemolysin Using Plant Essential Oils

AM El-Baz, RA Mosbah, RM Goda, B Mansour… - Antibiotics, 2021 - mdpi.com
Candida albicans is the causative agent of fatal systemic candidiasis. Due to limitations of
antifungals, new drugs are needed. The anti-virulence effect of plant essential oils (EOs) …

[HTML][HTML] Anti-Biofilm Activity of Cannabidiol against Candida albicans

M Feldman, RV Sionov, R Mechoulam, D Steinberg - Microorganisms, 2021 - mdpi.com
Candida albicans is a common fungal pathogen in humans. Biofilm formation is an important
virulence factor of C. albicans infections. We investigated the ability of the plant-derived …

[HTML][HTML] Turbinmicin inhibits Candida biofilm growth by disrupting fungal vesicle–mediated trafficking

M Zhao, F Zhang, R Zarnowski, K Barns… - The Journal of …, 2021 - Am Soc Clin Investig
The emergence of drug-resistant fungi has prompted an urgent threat alert from the US
Centers for Disease Control (CDC). Biofilm assembly by these pathogens further impairs …

[HTML][HTML] Analysis of pathogenic bacterial and yeast biofilms using the combination of synchrotron ATR-FTIR microspectroscopy and chemometric approaches

S Cheeseman, ZL Shaw, J Vongsvivut, RJ Crawford… - Molecules, 2021 - mdpi.com
Biofilms are assemblages of microbial cells, extracellular polymeric substances (EPS), and
other components extracted from the environment in which they develop. Within biofilms, the …

Persistent inhibition of Candida albicans biofilm and hyphae growth on titanium by graphene nanocoating

SV Agarwalla, K Ellepola, N Silikas, AHC Neto… - Dental Materials, 2021 - Elsevier
Objectives Candida albicanscolonizes biomaterial surfaces and are highly resistant to
therapeutics. Graphene nanocoating on titanium compromises initial biofilm formation …

The complex genetic basis and multilayered regulatory control of yeast pseudohyphal growth

A Kumar - Annual Review of Genetics, 2021 - annualreviews.org
Eukaryotic cells are exquisitely responsive to external and internal cues, achieving precise
control of seemingly diverse growth processes through a complex interplay of regulatory …

[HTML][HTML] The Flo adhesin family

RG Willaert, Y Kayacan, B Devreese - Pathogens, 2021 - mdpi.com
The first step in the infection of fungal pathogens in humans is the adhesion of the pathogen
to host tissue cells or abiotic surfaces such as catheters and implants. One of the main …

[HTML][HTML] Development of Chitosan-Based Surfaces to Prevent Single- and Dual-Species Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

M Lima, R Teixeira-Santos, LC Gomes, SI Faria… - Molecules, 2021 - mdpi.com
Implantable medical devices (IMDs) are susceptible to microbial adhesion and biofilm
formation, which lead to several clinical complications, including the occurrence of implant …