Insight into susceptibility genes associated with bipolar disorder: A systematic review

G Kalcev, A Preti, A Scano, G Orrù, MG Carta - European review for …, 2021 - iris.unito.it
Objective: Bipolar disorder (BD) is a severe disorder, and it is associated with an increased
risk of mortality. About 25% of patients with BD have attempted and 11% have died by …

[HTML][HTML] Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons

C Li, F Meng, JC Garza, J Liu, Y Lei, SA Kirov… - Molecular …, 2021 - nature.com
The adipocyte-derived hormone adiponectin has a broad spectrum of functions beyond
metabolic control. We previously reported that adiponectin acts in the brain to regulate …

Identifying patients with major depressive disorder based on tryptophan hydroxylase-2 methylation using machine learning algorithms

R Fan, T Hua, T Shen, Z Jiao, Q Yue, B Chen, Z Xu - Psychiatry research, 2021 - Elsevier
Objectives This study aimed to identify patients with major depressive disorder (MDD) by
developing different machine learning (ML) models based on tryptophan hydroxylase-2 …

[HTML][HTML] The GSK3-NRF2 axis in suicide

HO Kalkman - Psychiatry International, 2021 - mdpi.com
Mutations in the genes coding for tryptophan-hydrolase-2 and the scaffold protein FKBP5
are associated with an increased risk of suicide. The mutation in both cases enhances the …

Polymorphisms in the FKBP5 gene are associated with attention deficit and hyperactivity disorder in Korean children

HJ Kim, HJ Jin - Behavioural Brain Research, 2021 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a common and heritable childhood
psychiatric disorder. Recently, many studies reported a down-regulated hypothalamus …

TPH2: A Key Gene Risk Factor and Potential Therapy Target in Depression

X Zhang, Y Wang - E3S Web of Conferences, 2021 - e3s-conferences.org
Depression is a world-wide psychological disease and millions of people suffer from it. The
illness is basically characterized by low mood with some other diverse manifestations. The …

Genetische und neurobiologische Determinanten suizidalen Erlebens und Verhaltens

D Rujescu - Suizidales Erleben und Verhalten. Ein Handbuch …, 2021 - books.google.com
Hinweise auf eine familiäre Häufung suizidalen Verhaltens wurden bereits 1838 von
Esquirol beschrieben und in späteren Studien konkretisiert. So konnte in epidemiologischen …

Der Einfluss der Tryptophan-Hydroxylase 2 auf den Knochenstoffwechsel des Femurs am Rattenmodell

YJ Sogl - 2021 - jlupub.ub.uni-giessen.de
Osteoporose tritt vor allem im höheren Alter auf. Veränderungen im Knochenstoffwechsel
sind hauptsächlich im Rahmen von System-und Hormonerkrankungen untersucht worden …

[PDF][PDF] The GSK3-NRF2 Axis in Suicide. Psychiatry Int. 2021, 2, 108–119

HO Kalkman - 2021 - pdfs.semanticscholar.org
Mutations in the genes coding for tryptophan-hydrolase-2 and the scaffold protein FKBP5
are associated with an increased risk of suicide. The mutation in both cases enhances the …