Epigenetic mechanisms in memory and cognitive decline associated with aging and Alzheimer's disease
Epigenetic mechanisms, which include DNA methylation, a variety of post-translational
modifications of histone proteins (acetylation, phosphorylation, methylation, ubiquitination …
modifications of histone proteins (acetylation, phosphorylation, methylation, ubiquitination …
Females, but not males, require protein degradation in the hippocampus for contextual fear memory formation
K Martin, M Musaus, S Navabpour, A Gustin… - Learning & …, 2021 - learnmem.cshlp.org
Strong evidence supports a role for protein degradation in fear memory formation. However,
these data have been largely done in only male animals. Here, we found that following …
these data have been largely done in only male animals. Here, we found that following …
The circadian clock gene Per1 modulates context fear memory formation within the retrosplenial cortex in a sex-specific manner
MW Urban, C Lo, KK Bodinayake, CA Brunswick… - Neurobiology of learning …, 2021 - Elsevier
Context memory formation is a complex process that requires transcription in many
subregions of the brain including the dorsal hippocampus and retrosplenial cortex. One …
subregions of the brain including the dorsal hippocampus and retrosplenial cortex. One …