[HTML][HTML] Therapeutic potential of thymoquinone in triple-negative breast cancer prevention and progression through the modulation of the tumor microenvironment

GM Adinew, E Taka, B Mochona, RB Badisa… - Nutrients, 2021 - mdpi.com
To date, the tumor microenvironment (TME) has gained considerable attention in various
areas of cancer research due to its role in driving a loss of immune surveillance and …

Triangulating the pharmacological properties of thymoquinone in regulating reactive oxygen species, inflammation, and cancer: Therapeutic applications and …

CYH Phua, ZL Teoh, BH Goh, WH Yap, YQ Tang - Life Sciences, 2021 - Elsevier
Cancer is a heterogeneous disease with high morbidity and mortality rate involving changes
in redox balance and deregulation of redox signalling. For decades, studies have involved …

[HTML][HTML] Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK …

AF AlAsmari, M Alharbi, F Alqahtani, F Alasmari… - Antioxidants, 2021 - mdpi.com
Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

Spanlastics as an efficient delivery system for the enhancement of thymoquinone anticancer efficacy: Fabrication and cytotoxic studies against breast cancer cell lines

E Alaaeldin, M Mostafa, HF Mansour… - Journal of Drug Delivery …, 2021 - Elsevier
Thymoquinone (TQ), a pleiotropic compound isolated from the seeds of Nigella sativa has a
great potential as a chemotherapeutic agent against several cancers. However, its limited …

[HTML][HTML] Removal of microbial pathogens and anticancer activity of synthesized nano-thymoquinone from Nigella sativa seeds

P Gnanasekaran, A Roy, NS Natesh, V Raman… - … Technology & Innovation, 2021 - Elsevier
Nigella Sativa (N. sativa) also known as black cumin seed and their active component
thymoquinone are used as anti-inflammatory, antimicrobial and anticancer treatments. This …

Thymoquinone chemosensitizes human colorectal cancer cells to imatinib via uptake/efflux genes modulation

NA Thabet, D El‐Khouly… - Clinical and …, 2021 - Wiley Online Library
Imatinib (IM) is a pharmaceutical drug that inhibits tyrosine kinase enzymes that are
responsible for the activation of many proteins by signal transduction cascades as c‐Abl, c …

Antitumor Effects Of Phytochemicals Of Hot Three Plants On Gastric Adenocarcinoma

N Ragchaasuren, M Tumurkhuu, T Byambaa, U Bold… - bioRxiv, 2021 - biorxiv.org
ABSTRACT BACKGROUND Thymoquinone (TQ) and beta-sitosterol (BS), the bioactive
constituents derived from the medicinal plant Atragene sibirica L, Ranunculus repens L …

اثر متیل‌جاسمونات و سالیسیلیک‌اسید بر فعالیت آنتی‌اکسیدانتی، ترکیبات فنلی و فلاونوئیدی در کشت سلولی سیاه‌دانه (Nigella sativa)

ابراهیم‌زاده, سنجریان - سلول و بافت, 2021‎ - jct.araku.ac.ir
هدف: هدف این مطالعه القای کالوس و تولید سوسپانسیون سلولی از گیاه دارویی شناخته شده سیاه‌دانه
Nigella sativa)) و به‌دنبال آن تاثیر الیسیتورهای سالیسیلیکاسید و متیلجاسمونات برروی …

[引用][C] بررسی نقش تیموکینون در میزان القاء آپوپتوز توسط سیس پلاتین از طریق آسیب اکسیداتیو DNA در سلول‌های سرطانی Saos-2

احمدزاده اقدم‎ - دانشگاه علوم پزشکی تبریز، دانشکده …