[HTML][HTML] Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
KS Dittlau, EN Krasnow, L Fumagalli, T Vandoorne… - Stem Cell Reports, 2021 - cell.com
Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
[HTML][HTML] Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system
BM Maoz - APL bioengineering, 2021 - pubs.aip.org
The complexity of the human brain creates significant, almost insurmountable challenges for
neurological drug development. Advanced in vitro platforms are increasingly enabling …
neurological drug development. Advanced in vitro platforms are increasingly enabling …
Understanding, engineering, and modulating the growth of neural networks: An interdisciplinary approach
ABSTRACT A deeper understanding of the brain and its function remains one of the most
significant scientific challenges. It not only is required to find cures for a plethora of brain …
significant scientific challenges. It not only is required to find cures for a plethora of brain …
Subcellular Compartmentalization for Neurobiology: Focusing on the Axon
A functional nervous system integrates the coordinated activity of millions of individual
neurons and their tightly regulated communication with nonneuronal tissues. Here, we …
neurons and their tightly regulated communication with nonneuronal tissues. Here, we …
[PDF][PDF] Optogenetic and electrical investigation of network dynamics in patterned neuronal cultures
T Hondrich - 2021 - d-nb.info
Our nervous system is one of the most complex systems on earth. To investigate some of the
nervous system's basic principles, neuronal cell cultures provide a highly controllable …
nervous system's basic principles, neuronal cell cultures provide a highly controllable …
[PDF][PDF] Human motor units in microfluidic devices are impaired by</i> FUS<//i> mutations and improved by HDAC6 inhibition
KS Dittlau, EN Krasnow, L Fumagalli… - Stem Cell …, 2021 - lirias.kuleuven.be
Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
Identifying Candidate Biomarkers of Ionizing Radiation in Human Pulmonary Microvascular Lumens Using Microfluidics—A Pilot Study
LJ Millet, RJ Giannone, MS Greenwood, CM Foster… - Micromachines, 2021 - mdpi.com
The microvasculature system is critical for the delivery and removal of key nutrients and
waste products and is significantly damaged by ionizing radiation. Single-cell capillaries and …
waste products and is significantly damaged by ionizing radiation. Single-cell capillaries and …
Novel insights into axonal physiology through the development and use of new microelectrode array technologies
JCB Mateus - 2021 - search.proquest.com
The axon can be viewed as a neuronal structure capable of concurrently receiving,
processing, and transmitting information. This view contrasts with a limiting, but deeply …
processing, and transmitting information. This view contrasts with a limiting, but deeply …