Despite an increasing arsenal of anticancer therapies, many patients continue to have poor
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …

Background and purpose Asiatic acid is one of the active compounds isolated from Centella
asiatica and has been used to treat many diseases, including hypertension, pulmonary …

For a long time, the incidence and mortality of lung cancer have ranked first among all kinds
of cancers, of which the major type is non-small cell lung cancer (NSCLC). Until now …

Ovarian cancer (OC) is the most lethal of gynecological tumors in women. Tumor
metabolism has become a new opportunity in the treatment of tumors. Pyruvate …

TPGS approved by FDA can be used as a P-gp inhibitor to effectively reverse multi-drug
resistance (MDR) and as an anticancer agent for synergistic antitumor effects. However, the …

Preliminary bioassay-guided fractionation was performed to identify cytotoxic compounds
from Hechtia glomerata, a plant that is used in Mexican ethnomedicine. Organic and …

Cancer cells exhibit a rewired metabolism to meet their specific energy needs for cell
proliferation. Despite remarkable efforts to unravel how cancer cells reprogram their …