RAS oncogenes are among the most commonly mutated proteins in human cancers. They
regulate a wide range of effector pathways that control cell proliferation, survival …

Lymphangioma is a common type of congenital vascular disease in children with a broad
spectrum of clinical manifestations. The current classification of lymphangioma by …

High-risk neuroblastoma is an aggressive childhood cancer that is characterized by high
rates of chemoresistance and frequent metastatic relapse. A number of studies have …

Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs.
However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need …

Представленная дискуссионная гипотеза является попыткой размышления о роли
адаптивного иммунного ответа в канцерогенезе. Известен факт того, что большинство …

Living organisms create, copy, and make use of information, the content depending on the
level of organization. In cells, a network of signal chain proteins regulates gene expression …

The presented controversial hypothesis is an attempt to reflect on the role of the adaptive
immune response in carcinogenesis. It is a well-known fact that the most of the signaling …

Noonan syndrome (NS) and the clinically related NS with multiple lentiginous (NMLS) are
genetic conditions characterized by upregulated RAS mitogen activated protein kinase (RAS …

The RAS/RAF/MEK/ERK signaling pathway plays an important role throughout mammalian
development, from embryogenesis to tissue-specific cellular homeostasis and its aberrant …

RAS oncogenes are among the most commonly mutated proteins in human cancers. They
regulate a wide range of effector pathways that control cell proliferation, survival …