The evolving story of incretins (GIP and GLP‐1) in metabolic and cardiovascular disease: a pathophysiological update
MA Nauck, DR Quast, J Wefers… - Diabetes, Obesity and …, 2021 - Wiley Online Library
The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
Modulation of adipocyte metabolism by microbial short-chain fatty acids
KS May, LJ den Hartigh - Nutrients, 2021 - mdpi.com
Obesity and its complications—including type 2 diabetes, cardiovascular disease, and
certain cancers—constitute a rising global epidemic that has imposed a substantial burden …
certain cancers—constitute a rising global epidemic that has imposed a substantial burden …
[图书][B] Fish nutrition
RW Hardy, SJ Kaushik - 2021 - books.google.com
Fish Nutrition, Fourth Edition is an up-to-date, authoritative presentation of all key elements
of the nutrition of fish and crustaceans. As aquaculture is rapidly expanding, more than 200 …
of the nutrition of fish and crustaceans. As aquaculture is rapidly expanding, more than 200 …
Can we decrease epicardial and pericardial fat in patients with diabetes?
EM Muzurović, S Vujošević… - Journal of …, 2021 - journals.sagepub.com
Diabetes mellitus (DM) is a chronic and complex metabolic disorder and also an important
cause of cardiovascular (CV) disease (CVD). Patients with type 2 DM (T2DM) and obesity …
cause of cardiovascular (CV) disease (CVD). Patients with type 2 DM (T2DM) and obesity …
Liraglutide regulates lipid metabolism via FGF21-LKB1-AMPK-ACC1 pathway in white adipose tissues and macrophage of type 2 diabetic mice
N Zhang, C Liu, Y Zhang, D Xu, L Gui, Y Lu… - Biochemical and …, 2021 - Elsevier
Abstract Liraglutide (LRG), a glucagon-like peptide 1 analogue (GLP1A), could decrease
body mass of type 2 diabetes (T2DM), but the exact molecular mechanism of LRG has not …
body mass of type 2 diabetes (T2DM), but the exact molecular mechanism of LRG has not …
[HTML][HTML] Liraglutide improves lipid and carbohydrate metabolism of ovariectomized rats
JFA Model, MV Lima, R Ohlweiler, EL Vogt… - Molecular and cellular …, 2021 - Elsevier
Considering that post-menopausal women and ovariectomized rodents develop obesity
associated with increased visceral fat, this study was developed to investigate if liraglutide, a …
associated with increased visceral fat, this study was developed to investigate if liraglutide, a …
In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes
NC Chilelli, A Faggian, F Favaretto… - American Journal …, 2021 - journals.physiology.org
Glycation is one of the most important posttranslational modifications in cells and tissues
and gives rise to highly reactive species called advanced glycation end products (AGEs) …
and gives rise to highly reactive species called advanced glycation end products (AGEs) …
The methionine aminopeptidase 2 inhibitor, TNP-470, enhances the antidiabetic properties of sitagliptin in mice by upregulating xenin
The therapeutic mechanism of action of methionine aminopeptidase 2 (MetAP2) inhibitors
for obesity-diabetes has not yet been fully defined. Xenin, a K-cell derived peptide hormone …
for obesity-diabetes has not yet been fully defined. Xenin, a K-cell derived peptide hormone …
Direct effect of the synthetic analogue of glucagon-like peptide type 1, liraglutide, on mature adipocytes is realized through adenylate-cyclase-dependent enhancing of …
ED Mamontova, SS Michurina, IS Stafeev… - Biochemistry …, 2021 - Springer
Incretin hormones analogues, including glucagon-like peptide type 1 (GLP-1), exhibit
complex glucose-lowering, anorexigenic, and cardioprotective properties. Mechanisms of …
complex glucose-lowering, anorexigenic, and cardioprotective properties. Mechanisms of …
Characterization of the genetic architecture of BMI in infancy and early childhood reveals age-specific effects and implicates pathways involved in Mendelian obesity
To elucidate the role of common genetic variation on infant and child weight development,
we performed genome-wide association studies across 12 time points from birth to eight …
we performed genome-wide association studies across 12 time points from birth to eight …