Targeting histone modifications in bone and lung metastatic cancers
CM Edwards, RW Johnson - Current osteoporosis reports, 2021 - Springer
Abstract Purpose of Review Breast cancer frequently metastasizes to the bone and lung, but
the ability to treat metastatic tumor cells remains a pressing clinical challenge. Histone …
the ability to treat metastatic tumor cells remains a pressing clinical challenge. Histone …
FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036
Inhibition of the HER2/ERBB2 receptor is a keystone to treating HER2-positive
malignancies, particularly breast cancer, but a significant fraction of HER2-positive (HER2+) …
malignancies, particularly breast cancer, but a significant fraction of HER2-positive (HER2+) …
Histone deacetylase inhibitors (HDACi), the ongoing epigenetic agents to enhance chemotherapy sensitization
H Sun, J Song, M Sun, C Shan - Epigenetic Regulation in Overcoming …, 2021 - Elsevier
Epigenetic alterations play a pivotal role in tumor initiation and progression. Histone
deacetylases (HDACs) are a family of epigenetic enzymes that affect gene transcription by …
deacetylases (HDACs) are a family of epigenetic enzymes that affect gene transcription by …