DNA methylation in stress and depression: from biomarker to therapeutics
Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …
responses and increased vulnerability to depression. Abnormal DNAm is observed in …
[HTML][HTML] A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspring
J Scarborough, FS Mueller, U Weber-Stadlbauer… - Molecular …, 2021 - nature.com
Antenatal psychopathology negatively affects obstetric outcomes and exerts long-term
consequences on the offspring's wellbeing and mental health. However, the precise …
consequences on the offspring's wellbeing and mental health. However, the precise …
[HTML][HTML] Epigenetics and Early Life Stress: Experimental Brood Size Affects DNA Methylation in Great Tits (Parus major)
Early developmental conditions are known to have life-long effects on an individual's
behavior, physiology and fitness. In altricial birds, a majority of these conditions, such as the …
behavior, physiology and fitness. In altricial birds, a majority of these conditions, such as the …
Maternal stress during pregnancy affects activity, exploration and potential dispersal of daughters in an invasive fish
Highlights•Maternal stress during pregnancy can affect offspring development.•We
manipulated exposure of pregnant mosquitofish to a predatory bass model.•Maternal stress …
manipulated exposure of pregnant mosquitofish to a predatory bass model.•Maternal stress …
The influence of maternal glucocorticoids on offspring phenotype in high-and low-risk environments
Elevated maternal glucocorticoid levels during gestation can lead to phenotypic changes in
offspring via maternal effects. Although such effects have traditionally been considered …
offspring via maternal effects. Although such effects have traditionally been considered …
Sex-specific maternal programming of corticosteroid-binding globulin by predator odour
Predation is a key organizing force in ecosystems. The threat of predation may act to
programme the endocrine hypothalamic–pituitary–adrenal axis during development to …
programme the endocrine hypothalamic–pituitary–adrenal axis during development to …
Diet-Epigenome interactions: epi-drugs modulating the epigenetic machinery during cancer prevention
FE Pehlivan - Epigenetics to Optogenetics: A New Paradigm in …, 2021 - books.google.com
The roles of diet and environment on health have been known since ancient times. Cancer
is both a genetic and an epigenetic disease and a complex interplay mechanism of genetic …
is both a genetic and an epigenetic disease and a complex interplay mechanism of genetic …
Role of brain-derived neurotrophic factor in shaping the behavioural response to environmental stressors
E Badowska-Szalewska, G Lietzau, J Moryś… - Folia …, 2021 - journals.viamedica.pl
Brain-derived neurotrophic factor (BDNF) is an important neurotrophin involved in an
integration of the brain activity in physiological and pathological conditions, with formation of …
integration of the brain activity in physiological and pathological conditions, with formation of …
Preconception parental predator stress induces brain and behavioral changes in offspring
S Bhattacharya - 2021 - research.library.mun.ca
Brain and behaviour are shaped by experience. Recent data suggest that experiences of the
parents can be 'passed-on'to alter brain and behavior of future generations. Stress during …
parents can be 'passed-on'to alter brain and behavior of future generations. Stress during …
[HTML][HTML] Moderation of the transgenerational transference of antenatal stress-induced anxiety
O Burstein, N Simon, Y Simchon-Tenenbaum… - Translational …, 2021 - nature.com
Maternal stress has debilitating implications for both mother and child, including increased
risk for anxiety. The current COVID-19 pandemic escalates these phenomena, thus, urging …
risk for anxiety. The current COVID-19 pandemic escalates these phenomena, thus, urging …