Diabetes mellitus is a severe condition in which the pancreas produces inadequate insulin
or the insulin generated is ineffective for utilisation by the body; as a result, insulin therapy is …

Viral infections causing pandemics and chronic diseases are the main culprits implicated in
devastating global clinical and socioeconomic impacts, as clearly manifested during the …

Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

In this work, we introduce, for the first time, novel hybrid microneedle patches with
implantable poly (lactic-co-glycolic acid)(PLGA) tips aligned with hydrogel-forming …

Abstract Treatment of neovascular ocular diseases involves intravitreal injections of
therapeutic proteins using conventional hypodermic needles every 4–6 weeks. Due to the …

Osteoarthritis (OA) is a chronic disease that seriously impairs people's physical function and
quality of life. Triptolide (TP), as a promising anti-inflammatory drug for the treatment of OA …

3D printing is an emerging technology aiming towards personalized drug delivery, among
many other applications. Microneedles (MN) are a viable method for transdermal drug …

Customized microneedle arrays (CMNAs) hold great promise for precise transdermal
delivery in a minimally invasive manner. Currently, the fast customization of microneedle …

As a painless and minimally invasive method of self-administration, microneedle is very
promising to replace subcutaneous injection of insulin for type I diabetes treatment. Since …

Microneedles (MNs) are one of intriguing approach for efficient transdermal drug delivery
that penetrates the protective skin barrier in a painless and less invasive way. In recent …