Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies
JL Schwartz, KL Jones, GW Yeo - Critical reviews in biochemistry …, 2021 - Taylor & Francis
Dozens of incurable neurological disorders result from expansion of short repeat sequences
in both coding and non-coding regions of the transcriptome. Short repeat expansions …
in both coding and non-coding regions of the transcriptome. Short repeat expansions …
Ruthenium (II) Complex‐Based G‐quadruplex DNA Selective Luminescent 'Light‐up'Probe for RNase H Activity Detection
A bis‐heteroleptic ruthenium (II) complex, 1 [PF6] 2 of benzothiazole amide substituted 2,
2′‐bipyridine ligand (bmbbipy) has been synthesized for the selective detection of G …
2′‐bipyridine ligand (bmbbipy) has been synthesized for the selective detection of G …
Black chromatin is indispensable for accurate simulations of Drosophila melanogaster chromatin structure
I Tuszynska, P Bednarz, B Wilczynski - bioRxiv, 2021 - biorxiv.org
The interphase chromatin structure is extremely complex, precise and dynamic.
Experimental methods can only show the frequency of interaction of the various parts of the …
Experimental methods can only show the frequency of interaction of the various parts of the …
Examining the role of the hedgehog pathway in wound healing and exploring various therapeutics to rescue delayed wounds
JZQ Tang - 2021 - dr.ntu.edu.sg
This thesis is organised into two parts. The first part of the thesis investigated the role of the
Hedgehog pathway in dermal fibroblast functions in wound healing. Smoothened (Smo) …
Hedgehog pathway in dermal fibroblast functions in wound healing. Smoothened (Smo) …
Novel vectors and uses thereof
JD BURKE, F Candotti - 2021 - Google Patents
Provided is a viral particle comprising a genomic RNA suitable for delivering a
polynucleotide sequence of interest (SOI) into a cell and/or a subject. The genomic RNA …
polynucleotide sequence of interest (SOI) into a cell and/or a subject. The genomic RNA …