Retrosplenial cortex in spatial memory: focus on immediate early genes mapping

E Balcerek, U Włodkowska, R Czajkowski - Molecular Brain, 2021 - Springer
The ability to form, retrieve and update autobiographical memories is one of the most
fascinating features of human behavior. Spatial memory, the ability to remember the layout …

Drug-activated cells: From immediate early genes to neuronal ensembles in addiction

M Salery, A Godino, EJ Nestler - Advances in Pharmacology, 2021 - Elsevier
Beyond their rapid rewarding effects, drugs of abuse can durably alter an individual's
response to their environment as illustrated by the compulsive drug seeking and risk of …

The immediate early gene Arc is not required for hippocampal long-term potentiation

M Kyrke-Smith, LJ Volk, SF Cooke… - Journal of …, 2021 - Soc Neuroscience
Memory consolidation is thought to occur through protein synthesis-dependent synaptic
plasticity mechanisms such as long-term potentiation (LTP). Dynamic changes in gene …

In vivo imaging of immediate early gene expression dynamics segregates neuronal ensemble of memories of dual events

P Meenakshi, S Kumar, J Balaji - Molecular Brain, 2021 - Springer
Identification of neurons undergoing plasticity in response to external stimuli is one of the
pertinent problems in neuroscience. Immediate early genes (IEGs) are widely used as a …

FosGFP expression does not capture a sensory learning-related engram in superficial layers of mouse barrel cortex

J Lee, J Urban-Ciecko, E Park, M Zhu… - Proceedings of the …, 2021 - National Acad Sciences
Immediate-early gene (IEG) expression has been used to identify small neural ensembles
linked to a particular experience, based on the principle that a selective subset of activated …

The role of early visual experience in the development of spatial‐frequency preference in the primary visual cortex

N Nishio, K Hayashi, AW Ishikawa… - The Journal of …, 2021 - Wiley Online Library
Key points The mature functioning of the primary visual cortex depends on postnatal visual
experience, while the orientation/direction preference is established just after eye‐opening …

Tissue optical clearing for biomedical imaging: from in vitro to in vivo

T Yu, D Li, D Zhu - Optical Imaging in Human Disease and Biological …, 2021 - Springer
Tissue optical clearing technique provides a prospective solution for the application of
advanced optical methods in life sciences. This chapter firstly gives a brief introduction to …

Real-time imaging of Arc/Arg3.1 transcription ex vivo reveals input-specific immediate early gene dynamics

PJ Lituma, RH Singer, S Das, PE Castillo - bioRxiv, 2021 - biorxiv.org
The ability of neurons to process and store salient environmental features underlies
information processing in the brain. Long-term information storage requires synaptic …

一氧化碳有机荧光探针和光控释放剂研究进展

李勇, 王栩, 解希雷, 张建, 唐波 - 化学学报, 2021 - sioc-journal.cn
摘要一氧化碳(CO) 是人体内重要的气体信号分子, 在多种重要的生理病理代谢活动中起着关键
性的调控作用, 被认为是具有广泛医学应用前景的药物活性分子. CO 生理学效应与其浓度 …

Real-time visualization of mRNA synthesis during memory formation in live animals

BH Lee, JY Shim, HC Moon, DW Kim, J Kim, JS Yook… - bioRxiv, 2021 - biorxiv.org
Memories are thought to be encoded in populations of neurons called memory trace or
engram cells. However, little is known about the dynamics of these cells because of the …