Currently, for seemingly every type of cancer, dysregulated levels of non-coding RNAs
(ncRNAs) are reported and non-coding transcripts are expected to be the next class of …

The metabolic change of tumor cells is an extremely complicated process that involves the
intersection and integration of various signal pathways. Compared with normal tissues …

Transcriptional regulation by Wnt signalling is primarily thought to be accomplished by a
complex of β-catenin and TCF family transcription factors (TFs). Although numerous studies …

Background Familial adenomatous polyposis is an inherited genetic disease, characterized
by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis …

Colorectal cancer (CRC) is one of the most common malignancies globally, and the
morbidity and mortality rates associated with it are among the highest around the world. Not …

Signaling pathways that regulate homeostasis and regeneration are found to be
deregulated in various human malignancies. Accordingly, attempts have been made to …

Simple Summary A relevant proportion of colorectal cancer patients diagnosed at young age
and/or with family history of that type of cancer do not carry germline mutations in know …

Vascular endothelial growth factor (VEGF) is one of the most important regulators of
angiogenesis. Several single nucleotide polymorphisms (SNPs) are associated with the …

Gastric cancer is a common malignant tumor of the digestive system. Its occurrence and
development are the result of a combination of genetic, environmental, and microbial factors …

Though additive forms of heritability are primarily studied in genetics, nonlinear, non‐
additive gene–gene interactions, that is, epistasis, could explain a portion of the missing …