Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …

M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Metformin for diabetes prevention: update of the evidence base

U Hostalek, I Campbell - Current medical research and opinion, 2021 - Taylor & Francis
We have conducted a narrative review based on a structured search strategy, focusing on
the effects of metformin on the progression of non-diabetic hyperglycemia to clinical type 2 …

[HTML][HTML] Type 2 diabetes prevention focused on normalization of glycemia: a two-year pilot study

AL McKenzie, SJ Athinarayanan, JJ McCue, RN Adams… - Nutrients, 2021 - mdpi.com
The purpose of this study is to assess the effects of an alternative approach to type 2
diabetes prevention. Ninety-six patients with prediabetes (age 52 (10) years; 80% female; …

[HTML][HTML] Dapagliflozin, metformin, monotherapy or both in patients with metabolic syndrome

L Cheng, Q Fu, L Zhou, Y Fan, F Liu, Y Fan, X Zhang… - Scientific Reports, 2021 - nature.com
The present study evaluated the effects of dapagliflozin, a SGLT2 inhibitor, or dapagliflozin
plus metformin versus metformin monotherapy in patients with metabolic syndrome. This …

[HTML][HTML] Metformin use and cognitive function in older adults with type 2 diabetes following a Mediterranean diet intervention

N Soldevila-Domenech, A Cuenca-Royo… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: Both adherence to the Mediterranean diet (MedDiet) and the use
of metformin could benefit the cognitive performance of individuals with type 2 diabetes, but …

[PDF][PDF] Role of vitamin B12 and folate in metabolic syndrome

T Ashok, H Puttam, VCA Tarnate, S Jhaveri… - Cureus, 2021 - cureus.com
Metabolic syndrome (MS) is a collection of pathological metabolic conditions that includes
insulin resistance, central or abdominal obesity, dyslipidemia, and hypertension. It affects …

Why are individuals with diabetes less active? The mediating role of physical, emotional, and cognitive factors

B Cheval, S Maltagliati, S Sieber… - Annals of Behavioral …, 2021 - academic.oup.com
Background Despite the key role of physical activity in the management of diabetes, many
individuals with diabetes do not engage in the recommended levels of physical activity …

[HTML][HTML] Clinical Efficacy of Brown Seaweeds Ascophyllum nodosum and Fucus vesiculosus in the Prevention or Delay Progression of the Metabolic Syndrome: A …

E Keleszade, M Patterson, S Trangmar, KJ Guinan… - Molecules, 2021 - mdpi.com
Metabolic syndrome (MetS) is a global public health problem affecting nearly 25.9% of the
world population characterised by a cluster of disorders dominated by abdominal obesity …

[HTML][HTML] Effect of metformin on lipid profiles of type 2 diabetes mellitus: a meta-analysis of randomized controlled trials

SW Gillani, N Ghayedi, P Roosta… - Journal of Pharmacy …, 2021 - journals.lww.com
Objective: The study aimed to perform a meta-analysis on randomised controlled trials to
investigate the effect of metformin on lipid profiles among type 2 diabetes mellitus patients …

Insulin resistance limits corneal nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control

G Ponirakis, MA Abdul‐Ghani… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction This study aimed to investigate whether insulin resistance (IR) in
individuals with type 2 diabetes undergoing intensive glycemic control determines the extent …