Advances in systemic therapy for non-small cell lung cancer

M Miller, N Hanna - Bmj, 2021 - bmj.com
Lung cancer remains a leading cause of cancer related mortality worldwide. Despite
numerous advances in treatments over the past decade, non-small cell lung cancer …

Stress and cancer: mechanisms, significance and future directions

A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Geriatric assessment–driven intervention (GAIN) on chemotherapy-related toxic effects in older adults with cancer: a randomized clinical trial

D Li, CL Sun, H Kim, E Soto-Perez-de-Celis… - JAMA …, 2021 - jamanetwork.com
Importance Although geriatric assessment–driven intervention improves patient-centered
outcomes, its influence on chemotherapy-related toxic effects remains unknown. Objective …

[HTML][HTML] Paracetamol: a review of guideline recommendations

U Freo, C Ruocco, A Valerio, I Scagnol… - Journal of clinical …, 2021 - mdpi.com
Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

Management of dyspnea in advanced cancer: ASCO guideline

D Hui, K Bohlke, T Bao, TC Campbell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide guidance on the clinical management of dyspnea in adult patients
with advanced cancer. METHODS ASCO convened an Expert Panel to review the evidence …

Effectiveness of integrated palliative and oncology care for patients with acute myeloid leukemia: a randomized clinical trial

A El-Jawahri, TW LeBlanc, A Kavanaugh… - JAMA …, 2021 - jamanetwork.com
Importance Patients with acute myeloid leukemia (AML) receiving intensive chemotherapy
experience substantial decline in their quality of life (QOL) and mood during their …

[HTML][HTML] Ovarian cancer

T Arora, S Mullangi, MR Lekkala - 2021 - europepmc.org
Objectives: Describe the epidemiology of ovarian cancer. Review the evaluation of a patient
with suspected ovarian cancer. Summarize the treatment options of ovarian cancer. Outline …

Early interdisciplinary supportive care in patients with previously untreated metastatic esophagogastric cancer: a phase III randomized controlled trial

Z Lu, Y Fang, C Liu, X Zhang, X Xin, Y He… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Effective interventions to improve prognosis in metastatic esophagogastric
cancer (EGC) are urgently needed. We assessed the effect of the early integration of …

Hospital-free days: a pragmatic and patient-centered outcome for trials among critically and seriously ill patients

CL Auriemma, SP Taylor, MO Harhay… - American Journal of …, 2021 - atsjournals.org
Hospital-free days (HFDs) is increasingly selected as the primary or secondary outcome in
clinical trials among critically and seriously ill patients. This outcome measure, alternatively …

Effect of an oncology nurse–led primary palliative care intervention on patients with advanced cancer: the CONNECT cluster randomized clinical trial

Y Schenker, AD Althouse, M Rosenzweig… - JAMA internal …, 2021 - jamanetwork.com
Importance Guidelines recommend early specialty palliative care for all patients with
advanced cancer, but most patients lack access to such services. Objective To assess the …