Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …

Osteoimmunity is involved in regulating the balance of bone remodeling and resorption, and
is essential for maintaining normal bone morphology. The interaction between immune cells …

Despite the widespread observations on the osteogenic effects of magnesium ion (Mg2+),
the diverse roles of Mg2+ during bone healing have not been systematically dissected …

The dual functional implants of antibacteria and osteointegration are highly demanded in
orthopedic and dentistry, especially for patients who suffer from diabetes or osteoporosis …

Imbalance between osteoblasts and osteoclasts accounts for the incidence and
deterioration of postmenopausal osteoporosis. Abnormally elevated RANKL and TNF-α …

Macrophage has been gradually recognized as a central regulator in tissue regeneration,
and the study of how macrophage mediates biomaterials-induced bone regeneration …

Materials based on Mg2+-containing phosphates are gaining great relevance in the field of
bone tissue repair via regenerative medicine methods. Magnesium ions, together with …

In rheumatoid arthritis (RA), inflammatory cytokines play a pivotal role in triggering abnormal
osteoclastogenesis leading to articular destruction. Recent studies have demonstrated …

Formation of mature bone-resorbing cells through osteoclastogenesis is required for the
continuous remodeling and repair of bone tissue. In aging and disease this process may …

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse drug
effect. There are multiple hypotheses to explain the development of MRONJ. Reduced bone …