Placental extracellular vesicles and pre‐eclampsia

J Schuster, SB Cheng, J Padbury… - American journal of …, 2021 - Wiley Online Library
Pre‐eclampsia is a hypertensive disease of pregnancy characterized by new‐onset
hypertension, with either proteinuria and/or organ dysfunction. Pre‐eclampsia is a leading …

[HTML][HTML] Angiogenic properties of placenta-derived extracellular vesicles in normal pregnancy and in preeclampsia

N Gebara, Y Correia, K Wang, B Bussolati - International journal of …, 2021 - mdpi.com
Angiogenesis is one of the main processes that coordinate the biological events leading to a
successful pregnancy, and its imbalance characterizes several pregnancy-related diseases …

[HTML][HTML] Cytokine imprint in preeclampsia

K Stefańska, M Zieliński, M Jankowiak… - Frontiers in …, 2021 - frontiersin.org
The hallmark of preeclampsia (PE) is a shift toward persistent inflammatory response,
accompanied by endothelial dysfunction. The driving forces in PE are proinflammatory …

Syncytiotrophoblast stress in early onset preeclampsia: The issues perpetuating the syndrome

I Carrasco-Wong, M Aguilera-Olguín… - Placenta, 2021 - Elsevier
Preeclampsia is a pregnancy-specific syndrome characterized by a sudden increase in
blood pressure accompanied by proteinuria and/or maternal multi-system damage …

[HTML][HTML] Syncytiotrophoblast extracellular vesicles from late-onset preeclampsia placentae suppress pro-inflammatory immune response in THP-1 macrophages

T Awoyemi, C Motta-Mejia, W Zhang, L Kouser… - Frontiers in …, 2021 - frontiersin.org
Syncytiotrophoblast derived Extracellular Vesicles (STBEV) from normal pregnancy (NP)
have previously been shown to interact with circulating monocytes and B cells and induce …

[HTML][HTML] Endoglin in the spotlight to treat cancer

T González Muñoz, AT Amaral… - International Journal of …, 2021 - mdpi.com
A spotlight has been shone on endoglin in recent years due to that fact of its potential to
serve as both a reliable disease biomarker and a therapeutic target. Indeed, endoglin has …

Extracellular vesicles and their potential role inducing changes in maternal insulin sensitivity during gestational diabetes mellitus

S Nair, V Ormazabal, M Lappas… - American Journal of …, 2021 - Wiley Online Library
Gestational diabetes mellitus (GDM) is one of the most common endocrine disorders during
gestation and affects around 15% of all pregnancies worldwide, paralleling the global …

Roles of exosomes-derived lncRNAs in preeclampsia

R Gong, AM Nuh, H Cao, M Ma - … Journal of Obstetrics & Gynecology and …, 2021 - Elsevier
Preeclampsia is a pregnancy-specific hypertensive syndrome, which seriously threatens the
safety of mother and infant. However, there is still no accurate biomarkers for the diagnosis …

[HTML][HTML] Extracellular vesicles and antiphospholipid syndrome: state-of-the-art and future challenges

U Štok, S Čučnik, S Sodin-Šemrl, P Žigon - International Journal of …, 2021 - mdpi.com
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by
thromboembolism, obstetric complications, and the presence of antiphospholipid antibodies …

Antiphospholipid antibodies and extracellular vesicles in pregnancy

M Tong, BW Tsai, LW Chamley - American Journal of …, 2021 - Wiley Online Library
Antiphospholipid antibodies (aPL) are autoantibodies that target phospholipid‐binding
proteins, such as β2 glycoprotein I (β2GPI), and can induce thrombosis systemically, as well …