Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn's disease

G Chevalier, A Laveissière, G Desachy, N Barnich… - Microbiome, 2021 - Springer
Abstract Background An Escherichia coli (E. coli) pathotype with invasive properties, first
reported by Darfeuille-Michaud and termed adherent-invasive E. coli (AIEC), was shown to …

Escherichia coli Affects Expression of Circadian Clock Genes in Human Hepatoma Cells

U Kovač, Z Žužek, L Raspor Dall'Olio, K Pohar, A Ihan… - Microorganisms, 2021 - mdpi.com
Recent research has indicated that dysbiosis of the gut microbiota can lead to an altered
circadian clock of the mammalian host. Herein we developed an original system that allows …

The soluble cytoplasmic tail of CD45 regulates T‐cell activation via TLR4 signaling

A Puck, S Künig, M Modak, L May… - European Journal of …, 2021 - Wiley Online Library
The soluble cytoplasmic tail of CD45 (ct‐CD45) is a cleavage fragment of CD45, that is
generated during the activation of human phagocytes. Upon release to the extracellular …