Sex and gender in asthma
NU Chowdhury, VP Guntur… - European …, 2021 - Eur Respiratory Soc
Asthma is a heterogenous disease, and its prevalence and severity are different in males
versus females through various ages. As children, boys have an increased prevalence of …
versus females through various ages. As children, boys have an increased prevalence of …
Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
CV Breton, R Landon, LG Kahn, MB Enlow… - Communications …, 2021 - nature.com
Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …
influences that may impact health outcomes directly or via interactions with the genome or …
Socioeconomic disadvantage and the pace of biological aging in children
METHODS: Saliva DNA methylation and socioeconomic circumstances were measured in
N= 600 children and adolescents aged 8 to 18 years (48% female) participating in the Texas …
N= 600 children and adolescents aged 8 to 18 years (48% female) participating in the Texas …
[HTML][HTML] The early-life exposome and epigenetic age acceleration in children
P de Prado-Bert, C Ruiz-Arenas, M Vives-Usano… - Environment …, 2021 - Elsevier
The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …
proposed as one of the underlying biological mechanisms. We investigated the association …
Prenatal air pollution exposure and neurodevelopment: a review and blueprint for a harmonized approach within ECHO
Background Air pollution exposure is ubiquitous with demonstrated effects on morbidity and
mortality. A growing literature suggests that prenatal air pollution exposure impacts …
mortality. A growing literature suggests that prenatal air pollution exposure impacts …
Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence
DNA methylation (DNAm) is known to play a pivotal role in childhood health and
development, but a comprehensive characterization of genome-wide DNAm trajectories …
development, but a comprehensive characterization of genome-wide DNAm trajectories …
Epigenetic alterations of maternal tobacco smoking during pregnancy: a narrative review
In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …
addition to being associated with later impairment in child's development. Epigenetic …
DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother–newborn pairs
Background Maternal smoking affects more than half a million pregnancies each year in the
US and is known to result in fetal growth restriction as measured by lower birthweight and its …
US and is known to result in fetal growth restriction as measured by lower birthweight and its …
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of
genetic, stochastic, and environmental influences associated with aggression. Here, we …
genetic, stochastic, and environmental influences associated with aggression. Here, we …
Impact of vitamin C supplementation on placental DNA methylation changes related to maternal smoking: association with gene expression and respiratory outcomes
LE Shorey-Kendrick, CT McEvoy, SM O'Sullivan… - Clinical …, 2021 - Springer
Background Maternal smoking during pregnancy (MSDP) affects development of multiple
organ systems including the placenta, lung, brain, and vasculature. In particular, children …
organ systems including the placenta, lung, brain, and vasculature. In particular, children …