Ubiquitin ligase redundancy and nuclear-cytoplasmic localization in yeast protein quality control
CA Breckel, M Hochstrasser - Biomolecules, 2021 - mdpi.com
The diverse functions of proteins depend on their proper three-dimensional folding and
assembly. Misfolded cellular proteins can potentially harm cells by forming aggregates in …
assembly. Misfolded cellular proteins can potentially harm cells by forming aggregates in …
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins
G Tian, C Hu, Y Yun, W Yang, W Dubiel… - The EMBO …, 2021 - embopress.org
Exposure to heat stress triggers a well‐defined acute response marked by HSF1‐dependent
transcriptional upregulation of heat shock proteins. Cells allowed to recover acquire …
transcriptional upregulation of heat shock proteins. Cells allowed to recover acquire …
Ribosome‐associated quality control mediates degradation of the premature translation termination product Orf1p of ODC antizyme mRNA
AK Pradhan, G Kandasamy, U Chatterjee… - FEBS …, 2021 - Wiley Online Library
Decoding of OAZ1 (O rnithine decarboxylase A nti Z yme 1) mRNA, which harbours two
open reading frames (ORF1 and ORF2) interrupted by a naturally occurring Premature …
open reading frames (ORF1 and ORF2) interrupted by a naturally occurring Premature …
[图书][B] Proteostasis beyond chaperones-Auxiliary systems in the management of damaged proteins
R Josefson - 2021 - gupea.ub.gu.se
Aging entails loss of functionality and increased risk of death, even for unicellular organisms,
such as the yeast Saccharomyces cerevisiae. On a cellular level, aging is accompanied by …
such as the yeast Saccharomyces cerevisiae. On a cellular level, aging is accompanied by …
Molecular characterization of the recruitment machinery for amyloid aggregates to the Insoluble Protein Deposit (IPOD) in Saccharomyces cerevisiae
A Prakash - 2021 - archiv.ub.uni-heidelberg.de
Increasing evidence suggests that the accumulation of misfolded protein species into
specific spatially separated deposition sites is a cytoprotective response of the cell. Yeast …
specific spatially separated deposition sites is a cytoprotective response of the cell. Yeast …
[图书][B] On chaperone co-operation in temporal and spatial protein quality control
R Andersson - 2021 - gupea.ub.gu.se
In order for a protein to be able to function correctly it needs to adopt its proper fold. Because
of this, protein quality control (PQC) is vital at every level of cellular function. The central …
of this, protein quality control (PQC) is vital at every level of cellular function. The central …
tRNA Regulation in Humans: The cellular effect of a pathological HARS Y454S mutation
R Kenana - 2021 - search.proquest.com
Abstract tRNAs are the adapter molecules involved in translating the genetic code into
functional protein in a living cell. tRNAs are charged with their cognate amino acids-by …
functional protein in a living cell. tRNAs are charged with their cognate amino acids-by …