[HTML][HTML] Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation

Q Lv, Y Xing, J Liu, D Dong, Y Liu, H Qiao… - … Pharmaceutica Sinica B, 2021 - Elsevier
Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates
with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 …

Cytotoxic Guaianolide Sesquiterpenoids from Ainsliaea fragrans

N Ding, J Wang, J Liu, Y Zhu, S Hou… - Journal of Natural …, 2021 - ACS Publications
Twelve guaianolide-type sesquiterpene oligomers with diverse structures were isolated from
the whole plants of Ainsliaea fragrans, including a novel trimer (1) and two new dimers (2 …

Dendrocrepidamine, a novel octahydroindolizine alkaloid from the roots of Dendrobium crepidatum

XQ Ding, YQ Zou, J Liu, XC Wang, Y Hu… - Journal of Asian …, 2021 - Taylor & Francis
A novel octahydroindolizine alkaloid, named dendrocrepidamine (1) with an unusual 18, 19,
19′-cyclopropanone-dendrocrepine skeleton, was isolated from the ethanol extract of the …

Structurally Diverse Polycyclic Salicylaldehyde Derivative Enantiomers from a Marine-Derived Fungus Eurotium sp. SCSIO F452

WM Zhong, XY Wei, YC Chen, Q Zeng, JF Wang… - Marine Drugs, 2021 - mdpi.com
To enlarge the chemical diversity of Eurotium sp. SCSIO F452, a talented marine-derived
fungus, we further investigated its chemical constituents from a large-scale fermentation with …

Myrrhterpenes A and B, anti-inflammatory cadinane sesquiterpenes from the resin of Commiphora myrrha

S Bao, C Li, H Li, J Wang, J Luan, Y Zhang, L Chen… - Phytochemistry …, 2021 - Elsevier
Two new cadinane sesquiterpenes named myrrhterpenes A and B (1, 2), along with
eighteen known analogs were isolated from the resin of Commiphora myrrha. Their …

Achyrophenols A–F: Polycyclic Polyphenol Lactone Skeletons and a Nor-Ursane-Type Triterpenoid from Achyrocline Satureioides

S Wang, D Zhang, J Zhu, H Liu, B Li… - The Journal of Organic …, 2021 - ACS Publications
Two novel derivatives of 2-methyl-1-(2, 3, 4, 6-tetrahydroxyphenyl) propan-1-one and (S)-2-
methyl-1-(2, 3, 4, 6-tetrahydroxyphenyl) butan-1-one (1 and 2), four novel six-membered …

Survey of natural products reported by Asian research groups in 2020

YF Liu, SS Yu - Journal of Asian Natural Products Research, 2021 - Taylor & Francis
The new natural products reported in 2020 in peer-reviewed articles in journals with good
reputations were reviewed and analyzed. The advances made by Asian research groups in …