[HTML][HTML] The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Obesity and aging: Molecular mechanisms and therapeutic approaches

AL Santos, S Sinha - Ageing Research Reviews, 2021 - Elsevier
The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Common and novel markers for measuring inflammation and oxidative stress ex vivo in research and clinical practice—which to use regarding disease outcomes?

A Menzel, H Samouda, F Dohet, S Loap, MS Ellulu… - Antioxidants, 2021 - mdpi.com
Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …

Human placental transcriptome reveals critical alterations in inflammation and energy metabolism with fetal sex differences in spontaneous preterm birth

YC Lien, Z Zhang, Y Cheng, E Polyak, L Sillers… - International Journal of …, 2021 - mdpi.com
A well-functioning placenta is crucial for normal gestation and regulates the nutrient, gas,
and waste exchanges between the maternal and fetal circulations and is an important …

[HTML][HTML] Crosstalk between PPARs and gut microbiota in NAFLD

L Wu, J Li, J Feng, J Ji, Q Yu, Y Li, Y Zheng… - Biomedicine & …, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disorder in
both China and worldwide. It ranges from simple steatosis and progresses over time to …

Relevance of peroxisome proliferator activated receptors in multitarget paradigm associated with the endocannabinoid system

A Lago-Fernandez, S Zarzo-Arias, N Jagerovic… - International Journal of …, 2021 - mdpi.com
Cannabinoids have shown to exert their therapeutic actions through a variety of targets.
These include not only the canonical cannabinoid receptors CB1R and CB2R but also …

Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Attenuates Metabolic Alterations in Mice Fed a High-Fat Diet through Its Anti-Inflammatory and …

T Vezza, J Garrido-Mesa, P Diez-Echave… - Nutrients, 2021 - mdpi.com
Background: Propyl propane thiosulfonate (PTSO) is an organosulfur compound from Allium
spp. that has shown interesting antimicrobial properties and immunomodulatory effects in …

Endocannabinoid system and tumour microenvironment: New intertwined connections for anticancer approaches

M Iozzo, G Sgrignani, G Comito, P Chiarugi… - Cells, 2021 - mdpi.com
The tumour microenvironment (TME) is now recognised as a hallmark of cancer, since
tumour: stroma crosstalk supports the key steps of tumour growth and progression. The …

The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a …

M Yahay, Z Heidari, Z Allameh, R Amani - Lipids in Health and Disease, 2021 - Springer
Abstract Background Polycystic Ovarian Syndrome (PCOS) is one of the most common
endocrinopathies and metabolic disorders in women during their reproductive years. It is …

Anti‐adipogenesis and metabolism‐regulating effects of heat‐inactivated Streptococcus thermophilus MN‐ZLW‐002

X Kang, H Liang, Y Luo, Z Li, F He… - Letters in Applied …, 2021 - academic.oup.com
Metabolic syndrome and obesity have become serious threats to public health worldwide.
This study was conducted to evaluate the anti‐adipogenesis and metabolism‐regulating …