[HTML][HTML] Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies
A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …
Despite significant advances in recanalization strategies, patients are still at risk for …
[HTML][HTML] Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?
Y Qiu, C Zhang, A Chen, H Wang, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …
[HTML][HTML] Neuroinflammation as a key driver of secondary neurodegeneration following stroke?
SM Stuckey, LK Ong, LE Collins-Praino… - International Journal of …, 2021 - mdpi.com
Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …
[HTML][HTML] Neurogenesis after stroke: a therapeutic perspective
Stroke is a major cause of death and disability worldwide. Yet therapeutic strategies
available to treat stroke are very limited. There is an urgent need to develop novel …
available to treat stroke are very limited. There is an urgent need to develop novel …
[HTML][HTML] Cytokines as therapeutic targets for cardio-and cerebrovascular diseases
Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic
complications still account for substantial morbidity and mortality worldwide. In this context …
complications still account for substantial morbidity and mortality worldwide. In this context …
[HTML][HTML] Role of neuroinflammation and blood-brain barrier permutability on migraine
G Yamanaka, S Suzuki, N Morishita… - International journal of …, 2021 - mdpi.com
Currently, migraine is treated mainly by targeting calcitonin gene-related peptides, although
the efficacy of this method is limited and new treatment strategies are desired …
the efficacy of this method is limited and new treatment strategies are desired …
COVID‐19 and ischemic stroke
D Sagris, A Papanikolaou, A Kvernland… - European journal of …, 2021 - Wiley Online Library
Since the onset of the COVID‐19 pandemic, a substantial proportion of COVID‐19 patients
had documented thrombotic complications and ischemic stroke. Several mechanisms …
had documented thrombotic complications and ischemic stroke. Several mechanisms …
[HTML][HTML] Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response
L Pearce, SM Davidson, DM Yellon - Basic research in cardiology, 2021 - Springer
The benefits of remote ischaemic conditioning (RIC) have been difficult to translate to
humans, when considering traditional outcome measures, such as mortality and heart …
humans, when considering traditional outcome measures, such as mortality and heart …
Updating concepts on atherosclerotic inflammation: From pathophysiology to treatment
S Ministrini, F Carbone… - European Journal of …, 2021 - Wiley Online Library
Background Atherosclerosis is recognized as a systemic low‐grade inflammatory disease.
Furthermore, the dysregulation of the inflammatory response and its timely resolution is a …
Furthermore, the dysregulation of the inflammatory response and its timely resolution is a …
Interleukin‐22 Plays a Protective Role by Regulating the JAK2‐STAT3 Pathway to Improve Inflammation, Oxidative Stress, and Neuronal Apoptosis following Cerebral …
Y Dong, C Hu, C Huang, J Gao, W Niu… - Mediators of …, 2021 - Wiley Online Library
The interleukins (ILs) are a pluripotent cytokine family that have been reported to regulate
ischemic stroke and cerebral ischemia/reperfusion (I/R) injury. IL‐22 is a member of the IL …
ischemic stroke and cerebral ischemia/reperfusion (I/R) injury. IL‐22 is a member of the IL …