Alzheimer's disease (AD) is a progressive, neurodegenerative disorder that is characterized
by neurodegeneration, cognitive impairment, and an eventual inability to perform daily tasks …

Alzheimer's disease (AD) is the most common form of age-related dementia. Despite
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …

Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's
disease, but the functional brain mechanisms that support cognitive resilience remain …

Abstract Klotho-VS heterozygosity (KL-VShet) is associated with reduced risk of Alzheimer's
disease (AD). However, whether KL-VShet is associated with lower levels of pathologic tau …

Although abnormal accumulation of amyloid in the brain is an early biomarker of Alzheimer's
disease (AD), wide variation in cognitive trajectories during life can be seen in the setting of …

Emerging evidence indicates an important role for neuroinflammation in depression. Brief
maternal separation promotes resilience to depression in offspring, but relatively little is …

Alzheimer's disease (AD) is a complex disease that is mediated by numerous factors and
manifests in various forms. A systems biology approach to studying AD involves analyses of …

Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) is the most prevalent subtype of TDP-43 proteinopathy, affecting up to 1/3rd of aged …

Observing Alzheimer's disease (AD) pathological changes in vivo with neuroimaging
provides invaluable opportunities to understand and predict the course of disease …

Background: The concept of motor reserve explains the individual differences in motor
deficits despite similar degrees of nigrostriatal dopamine depletion in Parkinson's disease …