Substance use disorders (SUDs) are characterized by a compulsion to seek and consume
one or more substances of abuse, with a perceived loss of control and a negative emotional …

Repeated drug use can change dopamine (DA) function in ways that promote the
development and persistence of addiction, but in what direction? By one view, drug use …

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Background Loss of control over drug intake occurring in drug addiction is believed to result
from disruption of reward circuits, including reduced responsiveness to natural rewards (eg …

Accumulating clinical evidence shows that psychedelic therapy, by synergistically combining
psychopharmacology and psychological support, offers a promising transdiagnostic …

Abstract Purpose of Review While the treatment of addictive disorders proves to be
challenging, new treatment approaches that evolved around the concepts of mindfulness …

Objectives: This systematic review aimed to understand the current state of the art about the
effectiveness of mindfulness-based relapse prevention (MBRP) on individuals with …

Drug addiction is a chronic relapsing disorder, and a significant amount of research has
been devoted to understand the factors that contribute to the development, loss of control …

Cocaine is known to increase brain dopamine at supranormal levels in comparison to
alternative nondrug rewards. According to the dopamine hypothesis of addiction, this …

Interoception refers to the perception of the internal state of the body and is increasingly
being recognized as an important factor in mental health disorders. Drugs of abuse produce …