Colorectal cancer is a major public health problem. Unfortunately, currently, no effective
curative option exists for this type of malignancy. The most promising cancer treatment …

Checkpoint inhibitors, such as anti-PD-1/PD-L1 antibodies, have been shown to be
extraordinarily effective, but their durable response rate remains low, especially in colorectal …

Colorectal cancer (CRC) is one of the most common malignant tumours of the digestive
system, and most patients are already in an advanced stage at the time of diagnosis …

Colorectal cancer (CRC) is one of the most mortal cancers in the world. Multiple factors and
bio-processes are associated with in tumorigenesis and metastasis of CRC, including …

First‑line chemotherapy for men with metastatic castration‑resistant prostate cancer
(mCRPC) has been employed to improve overall survival (OS) and progression‑free survival …

Objective This study aimed to characterize the tumor-infiltrating T cells in moderately
differentiated colorectal cancer. Methods Using single-cell RNA sequencing data of isolated …

Approximately 40% of malignant melanomas are diagnosed in patients older than 65 years.
Elderly patients with melanoma present clinicopathological features related to a more …

Colorectal cancer (CRC) is one of the deadliest cancers in the world mainly due to
metastasis events. Despite improvements, the available treatment modalities for metastatic …

Background Gastrointestinal malignant cancers affect many sites in the intestinal tract,
including the colon. In this study, we purposed to improve prognostic predictions for colon …

Background. Colon cancer (CC) is a malignant tumor with a high incidence and poor
prognosis. Accumulating evidence shows that the immune signature plays an important role …