The evolving epidemiology of nasopharyngeal carcinoma

ET Chang, W Ye, YX Zeng, HO Adami - Cancer Epidemiology, Biomarkers & …, 2021 - AACR
Background: The epidemiology of nasopharyngeal carcinoma (NPC) has long been a
source of fascination due to the malignancy's striking geographic distribution, the …

Immunosuppressive agents and infectious risk in transplantation: managing the “net state of immunosuppression”

MB Roberts, JA Fishman - Clinical Infectious Diseases, 2021 - academic.oup.com
Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …

Tumor immunity and immunotherapy for HPV-related cancers

AA Shamseddine, B Burman, NY Lee, D Zamarin… - Cancer discovery, 2021 - AACR
Human papillomavirus (HPV) infection drives tumorigenesis in the majority of cervical,
oropharyngeal, anal, and vulvar cancers. Genetic and epidemiologic evidence has …

[HTML][HTML] Pretransplant solid organ malignancy and organ transplant candidacy: a consensus expert opinion statement

DP Al-Adra, L Hammel, J Roberts, ES Woodle… - American Journal of …, 2021 - Elsevier
Patients undergoing evaluation for solid organ transplantation (SOT) often have a history of
malignancy. Although the cancer has been treated in these patients, the benefits of …

[HTML][HTML] Transplant rejections associated with immune checkpoint inhibitors: a pharmacovigilance study and systematic literature review

LS Nguyen, S Ortuno, B Lebrun-Vignes… - European Journal of …, 2021 - Elsevier
Background Solid organ transplant recipients are at increased risk of cancer due to long-
term immunosuppression. Immune-checkpoint inhibitors (ICI) showed clinical benefits but …

Epidemiology of Kaposi's sarcoma

S Grabar, D Costagliola - Cancers, 2021 - mdpi.com
Simple Summary Kaposi's sarcoma is a rare tumor caused by human herpesvirus 8 in the
context of immunodeficiency, such as that induced by HIV infection or immunosuppressive …

Sebaceous carcinoma epidemiology and genetics: emerging concepts and clinical implications for screening, prevention, and treatment

MR Sargen, GJ Starrett, EA Engels, EK Cahoon… - Clinical Cancer …, 2021 - AACR
Sebaceous carcinoma is an aggressive skin cancer with a 5-year overall survival rate of
78% for localized/regional disease and 50% for metastatic disease. The incidence of this …

The long-term risk of lymphoma and skin cancer did not increase after topical calcineurin inhibitor use and phototherapy in a cohort of 25,694 patients with vitiligo

HJ Ju, JH Han, MS Kim, SH Lee, JW Shin… - Journal of the American …, 2021 - Elsevier
Background Topical calcineurin inhibitors have been used to treat vitiligo, either alone or in
combination with phototherapy; however, the long-term safety of these agents remains …

Checkpoint inhibitors and hepatotoxicity

SDH Malnick, A Abdullah, MG Neuman - Biomedicines, 2021 - mdpi.com
Uncontrolled immune response to a pathogen or any protein can lead to tissue damage and
autoimmune diseases, that represent aberrant immune responses of the individual to its own …

Sex differences in cancer risk and outcomes after kidney transplantation

A Buxeda, D Redondo-Pachón, MJ Pérez-Sáez… - Transplantation …, 2021 - Elsevier
Kidney transplant recipients (KTRs) experience a two-to four-fold increased risk of
developing and dying from cancer compared with the general population. High cancer risk …