Glucocorticoid steroids are widely used as immunomodulatory agents in acute and chronic
conditions. Glucocorticoid steroids such as prednisone and deflazacort are recommended …

There is a great demand for accurate non‐invasive measures to better define the natural
history of disease progression or treatment outcome in Duchenne muscular dystrophy …

Background This two‐part study explored the safety, feasibility, and efficacy of a mild–
moderate resistance isometric leg exercise program in ambulatory boys with Duchenne …

Objectives Quantitative MRI (qMRI) of muscles is a promising tool to measure disease
progression or to assess therapeutic effects in neuromuscular diseases. Longitudinal …

Introduction In this study we explored walking activity in a large cohort of boys with
Duchenne muscular dystrophy (DMD). Methods Step activity (monitored for 7 days) …

Microdystrophin gene transfer using recombinant adeno-associated virus serotype rh74
(rAAVrh74) driven by a skeletal and cardiac muscle-specific promoter with enhanced …

Aim: Using baseline data from a clinical trial of domagrozumab in Duchenne muscular
dystrophy, we evaluated the correlation between functional measures and quantitative MRI …

Chronic activation of NF-κB is a key driver of muscle degeneration and suppression of
muscle regeneration in Duchenne muscular dystrophy. Edasalonexent (CAT-1004) is an …

Background: Skeletal muscle biopsy is one of the gold standards in the diagnostic workup of
muscle disorders. By histopathologic analysis, characteristic features like inflammatory …

Purpose Aim of this study is to compare Quantitative Magnetic Resonance Imaging (qMRI)
measures between Becker Muscular Dystrophy (BMD) and Healthy Subjects (HS) and to …