[HTML][HTML] Burden of influenza B virus infection and considerations for clinical management

H Zaraket, AC Hurt, B Clinch, I Barr, N Lee - Antiviral Research, 2021 - Elsevier
Influenza B viruses cause significant morbidity and mortality, particularly in children, but the
awareness of their impact is often less than influenza A viruses partly due to their lack of …

[HTML][HTML] Mosaic hemagglutinin-based whole inactivated virus vaccines induce broad protection against influenza B virus challenge in mice

Y Liu, S Strohmeier, I González-Domínguez… - Frontiers in …, 2021 - frontiersin.org
Influenza viruses undergo antigenic changes in the immuno-dominant hemagglutinin (HA)
head domain, necessitating annual re-formulation of and re-vaccination with seasonal …

[HTML][HTML] A systematic review and meta-analysis of host genetic factors associated with influenza severity

N Van Goethem, C Danwang, N Bossuyt, H Van Oyen… - BMC genomics, 2021 - Springer
Background The severity of influenza disease can range from mild symptoms to severe
respiratory failure and can partly be explained by host genetic factors that predisposes the …

[HTML][HTML] Early oseltamivir treatment improves survival in critically ill patients with influenza pneumonia

G Moreno, A Rodríguez, J Sole-Violán… - ERJ open …, 2021 - Eur Respiratory Soc
Background The relationship between early oseltamivir treatment (within 48 h of symptom
onset) and mortality in patients admitted to intensive care units (ICUs) with severe influenza …

[HTML][HTML] Evaluation of the added value of viral genomic information for predicting severity of influenza infection

N Van Goethem, A Robert, N Bossuyt… - BMC infectious …, 2021 - Springer
Background The severity of an influenza infection is influenced by both host and viral
characteristics. This study aims to assess the relevance of viral genomic data for the …

Cortisol and perceived stress are associated with cytokines levels in patients infected with influenza B virus

CA Lopez-Acevo, E Arrendondo-Loza… - Cytokine, 2021 - Elsevier
Influenza B virus (IBV) causes respiratory infectious disease. Cytokines are important
immune mediators during infectious diseases. Cortisol and stress have been related to …

[PDF][PDF] Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages

C Gravel, A Muralidharan, A Duran, A Zetner, A Pfeifle… - Iscience, 2021 - cell.com
A quarter of all seasonal influenza cases are caused by type B influenza virus (IBV) that also
dominates periodically. Here, we investigated a recombinant adenovirus vaccine carrying a …

[HTML][HTML] Influenza B virus infection is enhanced upon heterotypic co-infection with influenza a virus

N Malausse, S van Der Werf, N Naffakh… - Frontiers in …, 2021 - frontiersin.org
Homotypic co-infections with influenza viruses are described to increase genetic population
diversity, to drive viral evolution and to allow genetic complementation. Less is known about …

[HTML][HTML] Conceptual causal framework to assess the effect of SARS-CoV-2 variants on COVID-19 disease severity among hospitalized patients

N Van Goethem, B Serrien, M Vandromme… - Archives of Public …, 2021 - Springer
Background SARS-CoV-2 strains evolve continuously and accumulate mutations in their
genomes over the course of the pandemic. The severity of a SARS-CoV-2 infection could …

Influenza B viruses: underestimated and overlooked

M Koutsakos, SJ Kent - Microbiology Australia, 2021 - CSIRO Publishing
Influenza B viruses circulate globally every year causing respiratory disease with significant
clinical and socio-economic impacts. IBV are considered exclusive human pathogens with …