Breast cancer therapeutics and biomarkers: past, present, and future approaches

J Schick, RP Ritchie, C Restini - Breast Cancer: Basic and …, 2021 - journals.sagepub.com
Breast cancer (BC) is the leading cause of cancer death in women and the second-most
common cancer. An estimated 281 550 new cases of invasive BC will be diagnosed in …

[HTML][HTML] The prognostic impact of retinoid X receptor and thyroid hormone receptor alpha in unifocal vs. multifocal/multicentric breast cancer

AZ Zehni, F Batz, A Vattai, T Kaltofen… - International Journal of …, 2021 - mdpi.com
The aim of this study was to assess the prognostic value of the steroid hormone receptor
expression, counting the retinoid X receptor (RXR) and thyroid hormone receptors (THRs) …

[HTML][HTML] Cytoplasmic localization of rxrα determines outcome in breast cancer

A Zati Zehni, F Batz, V Cavaillès, S Sixou, T Kaltofen… - Cancers, 2021 - mdpi.com
Simple Summary Considering the immense development of today's therapeutic approaches
in oncology towards customized therapy, this study aimed to assess the prognostic value of …

RNA‐seq reveals novel cancer‐selective and disease subtype‐independent mechanistic targets of withaferin A in human breast cancer cells

ER Hahm, SH Kim, KB Singh… - Molecular …, 2021 - Wiley Online Library
Withaferin A (WA) exhibits cancer chemopreventive efficacy in preclinical models
representative of two different subtypes of breast cancer. However, the mechanism (s) …

[HTML][HTML] Interleukin 15 and Eotaxin correlate with the outcome of breast cancer patients vice versa independent of CTC status

T Vilsmaier, HH Heidegger, L Schröder, E Trapp… - Archives of gynecology …, 2021 - Springer
Background Circulating tumor cells (CTC) in the peripheral blood in women with breast
cancer has been found to be an indicator of prognosis before the start of systemic treatment …

Efficacy and safety of endocrine therapy for breast-cancer prevention in high-risk premenopausal or postmenopausal women: a Bayesian network meta-analysis of …

R Sun, Y Chu, Y Gao, W Cheng, S Gao - Menopause, 2021 - journals.lww.com
Objective: This study aimed to evaluate the efficacy and safety of these drugs based on the
Bayesian network meta-analysis. Evidence review: Two researchers systematically and …

Osteoporosis Diagnosis and Management

R Pope, J Doback - Physician Assistant Clinics, 2021 - physicianassistant.theclinics.com
Osteoporosis (OP) is the most common bone disease in humans and has become a major
public health problem. It is characterized by low bone mass, deterioration of bone tissue and …

Systemic Treatment of Ductal Carcinoma In Situ of the Breast

E Crimini, C Corti, M Repetto, F Giugliano… - Chirurgia, 2021 - air.unimi.it
Ductal carcinoma in situ (DCIS) is a noninvasive breast cancer (BC), whose diagnosis
significatively increased with the diffusion of BC screening programs. DCIS actually …

Chemoprevention for Breast Cancer

R Watanuki, A Nagayama, T Hayashida… - Hereditary Breast and …, 2021 - Springer
Cancer chemoprevention is defined as the use of natural, synthetic, or biochemical agents to
reverse, suppress, or prevent carcinogenic processes in neoplastic diseases. Although the …

[PDF][PDF] Cytoplasmic Localization of RXRα Determines Outcome in Breast Cancer. Cancers 2021, 13, 3756

F Batz, V Cavaillès, S Sixou, T Kaltofen, S Keckstein… - 2021 - hal.science
The aim of this retrospective study was to assess the prognostic value of cytoplasmic versus
nuclear RXRα expression in breast cancer (BC) tissue samples and to correlate the results …