[HTML][HTML] Antioxidant-based therapy reduces early-stage intestinal ischemia-reperfusion injury in rats

G Gutiérrez-Sánchez, I García-Alonso… - Antioxidants, 2021 - mdpi.com
Intestinal ischemia-reperfusion injury (i-IRI) is a rare disorder with a high mortality rate,
resulting from the loss of blood flow to an intestinal segment. Most of the damage is triggered …

[HTML][HTML] Triclosan affects the expression of nitric oxide synthases (NOSs), peroxisome proliferator-activated receptor gamma (PPARγ), and nuclear factor kappa-light …

KA Szychowski, B Skóra, AK Wójtowicz - Toxicology in Vitro, 2021 - Elsevier
Triclosan (TCS) is a well-known compound that can be found in disinfectants, personal care
products. There is one publication concerning the involvement of PPARγ in the mechanism …

[HTML][HTML] Some aspects of role of nitric oxide in the mechanisms of hypertension (experimental study)

K Kakabadze, I Megreladze, N Khvichia… - Cardiology …, 2021 - ncbi.nlm.nih.gov
Background Modulation of endothelial function is a therapeutic option to reduce some of the
significant complications of hypertension. However, the relationship between endothelial …

Saussureae radix attenuates neuroinflammation in LPS‐stimulated mouse BV2 microglia via HO‐1/Nrf‐2 induction and inflammatory pathway inhibition

YC Oh, W Li, JG Choi - Mediators of Inflammation, 2021 - Wiley Online Library
The activation of microglial cells and their subsequent neuroinflammatory reactions are
related to various degenerative brain diseases. Therefore, the regulation of microglial cell …

Muscarinic regulation of the neuronal Na+/K+‐ATPase in rat hippocampus

S Mohan, MN Tiwari, M Stanojević… - The Journal of …, 2021 - Wiley Online Library
Key points Stimulation of postsynaptic muscarinic receptors was shown to excite principal
hippocampal neurons by modulating several membrane ion conductances. We show here …

[HTML][HTML] Clusterin enhances cell survival by suppressing neuronal nitric-oxide synthase expression in the rhodopsin S334ter-line3 retinitis pigmentosa model

A Vargas, KL Yamamoto, CM Craft, EJ Lee - Brain Research, 2021 - Elsevier
Environmental changes in the retina, including oxidative stress-induced cell death, influence
photoreceptor degeneration in Retinitis Pigmentosa (RP). Previously, we tested and …

[HTML][HTML] Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report)

P Erhardt, K Bachmann, D Birkett, M Boberg… - Pure and Applied …, 2021 - degruyter.com
This project originated more than 15 years ago with the intent to produce a glossary of drug
metabolism terms having definitions especially applicable for use by practicing medicinal …

[PDF][PDF] Muscarinic regulation of the neuronal Na/K-ATPase in rat hippocampus

S Mohan, MN Tiwari, M Stanojevic, Y Biala, Y Yaari - 2021 - researchgate.net
Stimulation of muscarinic cholinergic receptors on principal hippocampal neurons enhances
intrinsic neuronal excitability by modulating several membrane ion conductances. The …

Učinci pentadekapeptida BPC 157 i interakcija s NO–spojevima u eksperimentalnom modelu psihoze na štakorima

A Zemba Čilić - 2021 - dr.nsk.hr
Cilj ovog istraživanja bio je sistematično i podrobno istražiti učinke stabilnog
pentadekapeptida BPC 157 u interakciji s NO-spojevima u modelima psihoze i nuspojava …