Prostate cancer is featured by its heterogeneous nature, which indicates a different
prognosis. Castration-resistant prostate cancer (CRPC) is a hallmark of the treatment …

Glioma is the most common and aggressive tumor of the central nervous system. The
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …

Long noncoding RNAs (lncRNA) are involved in tumorigenesis and drug resistance.
However, the roles and underlying mechanisms of lncRNAs in colorectal cancer are still …

Abstract Switch/sucrose-nonfermentable (SWI/SNF) chromatin-remodeling complexes are
critical regulators of chromatin dynamics during transcription, DNA replication, and DNA …

Background NONO-TFE3 translocation renal cell carcinoma (NONO-TFE3 tRCC) is one
subtype of RCCs associated with Xp11. 2 translocation/TFE3 gene fusions RCC (Xp11. 2 …

Lymph node metastasis is one of the most malignant clinical features in patients with
esophageal squamous cell carcinoma (ESCC). Understanding the mechanism of lymph …

Little is known about noncoding tumor suppressor genes. An effective way to identify these
genes is by analyzing somatic copy number variation (CNV)-related noncoding genes. By …

Abstract Wild-type KRAS (KRAS WT) amplification has been shown to be a secondary
means of KRAS activation in cancer and associated with poor survival. Nevertheless, the …

During aging and neuromuscular diseases, there is a progressive loss of skeletal muscle
volume and function impacting mobility and quality of life. Muscle loss is often associated …

Abstract Rationale: Enhancer RNA (eRNA) bi-directionally expresses from enhancer region
and sense eRNA regulates adjacent mRNA in cis and in trans. However, it has remained …