Progesterone acts on neurons directly by activating its receptor and through metabolic
conversion to neurosteroids. There is emerging evidence that progesterone exerts excitatory …

Stress is a common seizure trigger in persons with epilepsy. The body's physiological
response to stress is mediated by the hypothalamic-pituitary-adrenal (HPA) axis and …

Super-refractory status epilepticus (SRSE) is a life-threatening neurological emergency with
high morbidity and mortality. It is defined as “status epilepticus (SE) that continues or recurs …

Current neuroscience research on neurosteroids and their synthetic analogues–neuroactive
steroids–clearly demonstrate their drug likeness in a variety of neurological and psychiatric …

Seizures, Status Epilepticus, and Continuous EEG in the Inte... : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

This S2k guideline on diagnosis and treatment of status epilepticus (SE) in adults is based
on the last published version from 2021. New definitions and evidence were included in the …

Abstract Diese S2k-Leitlinie (LL) zum Status epilepticus (SE) im Erwachsenenalter schreibt
die letzte DGN-LL zum SE von 2012 fort. Neue Definitionen und Evidenz wurden bei der …

Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously
demonstrated to be a potent neuroprotective compound in several biological models in vivo …

Neuroactive steroids have rapid, nongenomic effects on neuronal excitability. The effects in
humans are less clear. We compared seizure control and concentrations of neuroactive …

Objective We examined the clinical manifestations of acute encephalopathy (AE) and
identify risk factors for AE in children with tuberous sclerosis complex (TSC). Methods The …