Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Salt Handling and Blood Pressure Salt intake is associated with blood pressure, but the
relationship is complex. This review highlights the interplay among renal salt transport, salt …

Salt sensitivity refers to the physiological trait present in mammals, including humans, by
which the blood pressure (BP) of some members of the population exhibits changes parallel …

Glucocorticoids are steroid hormones with key roles in the regulation of many physiological
systems including energy homeostasis and immunity. However, chronic glucocorticoid …

The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for
cardiovascular diseases. It is now widely accepted that an experimental HSD can stimulate …

Aim We have reported earlier that a high salt intake triggered an aestivation‐like natriuretic‐
ureotelic body water conservation response that lowered muscle mass and increased blood …

Concomitant type 2 diabetes and chronic kidney disease increases the risk of heart failure.
Recent studies demonstrate beneficial effects of sodium-glucose cotransporter 2 (SGLT2) …

Chronic kidney disease (CKD) is associated with increased risk of cardiovascular (CV)
events, and the disease burden is rising rapidly. An important contributor to CV events and …

Sodium and water are the main determinants of body volume status and BP. Because
sodium and water are excreted by the kidneys, maintenance of volume homeostasis is …

Novel MRI techniques allow a noninvasive quantification of tissue sodium and reveal the
skin as a prominent compartment of sodium storage in health and disease. Since multiple …